Results 51 to 60 of about 731,585 (310)
Structure—Property Relationships of Aromatic Polyesters
KOBUNSHI RONBUNSHU, 2010 芳香族ポリエステル poly(ethylene terephthalate) (PET), poly(ethylene-2,6-naphthalate) (PEN), poly(trimethylene terephthalate) (PTT)のコンホメーション解析を，モデル化合物，ethylene glycol dibenzoate (EGDB)と trimethylene glycol dibenzoate (TMGDB)の分子軌道法(MO)計算とポリマーの高精度回転異性状態(RIS)法の計算を組合せて行った．両モデル化合物の MO 計算は，1H, 13C NMR 実験で求めた O-CH2 と CH2-CH2 結合の配座分率と電気複屈折測定で得られた分子 Kerr ...
SASANUMA, Yuji, SUZUKI, Nobuaki
openaire +2 more sources
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Quantitative structure–reactivity relationships for synthesis planning: The benzhydrylium case [PDF]
, 2023 Selective and feasible reactions are top targets in synthesis planning, both of which depend on the reactivity of the molecules involved. Mayr’s approach to quantifying reactivity has greatly facilitated the planning process, but reactivity parameters ...
Johannes V., Diedrich +3 more
core +1 more source
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
BioMedical Engineering OnLine, 2023 Background Bone tissue engineering, based on three-dimensional (3D) printing technology, has emerged as a promising approach to treat bone defects using scaffolds.
Zahra Yazdanpanah +5 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
New Strategies in Quantitative Structure-Activity Relationships. Applications to Adenosine Receptor Ligands [PDF]
, 2006 Over the last years, an increasing number of applications of QSAR (Quantitative Structure-Activity Relationships) appeared in the literature, not only in lead finding and lead optimization, but also in other fields related to drug discovery, such as ...
Borghini, Alice
core
Materials & DesignPredicting barrier properties of multilayer materials is essential for designing effective food packaging. Although resistance-based models are commonly used, their applicability to complex structures, such as polymer-coated paper/cardboard, remains ...
Allison Vercasson +4 more
doaj +1 more source
Computation of Vertex-Based Topological Descriptors of Organometallic Monolayers of TM3C12S12
Journal of Mathematics, 2021 Topological descriptors are mathematical values related to chemical structures which are associated with different physicochemical properties. The use of topological descriptors has a great contribution in the field of quantitative structure-property ...
Dalal Alrowaili +6 more
doaj +1 more source
Fractal and Fractional, 2022 Porous alumina was prepared by the sacrificial template approach using 30 vol.%, 50 vol.%, and 70 vol.% of carbon fibers and graphite as pore formers. In order to determine the pore size distribution, porosity, most probable pore size, and median pore ...
Xufu Wang, Chang Chen, Yubin Wang
doaj +1 more source