Results 71 to 80 of about 731,585 (310)
Fast conditional density estimation for quantitative structure-activity relationships [PDF]
, 2010 Many methods for quantitative structure-activity relationships (QSARs) deliver point estimates only, without quantifying the uncertainty inherent in the prediction.
Buchwald, Fabian +3 more
core +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Defect structure in nanomaterials / [PDF]
, 2012 Nanomaterials exhibit unique mechanical and physical properties compared to their coarse-grained counterparts, and are consequently a major focus of current scientific research.
Gubicza, Jeno,author.
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Structure-property relationships in polyether-urethane based solid polymer electrolytes [PDF]
, 1995 Structure-property relationships in polyether-urethane based solid polymer ...
J Hey (13746148) +4 more
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ComputationThis study aims to comprehensively evaluate the mechanical performance of dry-spun twisted carbon nanotube (CNT) yarns (CNTYs) subjected to uniaxial tensile load.
Aref Mehditabar +2 more
doaj +1 more source
Beilstein Journal of Nanotechnology, 2017 The exploitation of nanoscale size effects to create new nanostructured materials necessitates the development of an understanding of relationships between molecular structure, physical properties and material processing at the nanoscale.
Gheorghe Stan +7 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Tomato Skin as a Sustainable and Healthy Ingredient [PDF]
, 2011 Tomato skin can be recovered from tomato processing waste and alternative processes have been proposed for its non-traditional uses in food. Large-scale implementation of these processes could increase the sustainability of the tomato industry and ...
M. Corey, V. Lavelli
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