Statins, identified via the Comparative Toxicogenomics Database, promote monocytic differentiation and apoptosis in non‐APL AML cells by upregulating DPYSL2A through a KLF4‐dependent pathway. Mevalonate supplementation reversed these effects, indicating involvement of the mevalonate pathway.
Mina Noura +7 more
wiley +1 more source
New structural insights into Fe<sub>2</sub>P<sub>2</sub>O<sub>7</sub> - unravelling an unresolved dispute and three reversible phase transitions. [PDF]
Stöger B +7 more
europepmc +1 more source
Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
Robust Two-Dimensional Hydrogen-Bonded Organic Framework for Efficient Separation of C1–C3 Alkanes
Yunzhe Zhou +5 more
doaj +1 more source
Unveiling the ambient-condition structure of Sr<sub>2</sub>FeIrO<sub>6</sub>: a triclinic phase through synchrotron-based X-ray techniques and high pressure. [PDF]
Gallego-Parra S +11 more
europepmc +1 more source
We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
The Significant Impact of Lost Species' Identity, Number and Abundance on Functional Structure of Alpine Meadow. [PDF]
Yang Z +14 more
europepmc +1 more source
Structural and functional characterization of chitinase from carnivorous plant Drosera adelae
A class I chitinase from the carnivorous plant Drosera adelae was expressed and purified using a yeast system, revealing high enzymatic activity. Structural analyses of the catalytic and chitin‐binding domains identified key tyrosine residues involved in substrate binding, offering insights into the enzyme's adaptation for insect digestion.
Kazunari Yoneda +7 more
wiley +1 more source
Corrigendum to "Affective Polarization and Political Belief Systems: The Role of Political Identity, and the Content and Structure of Political Beliefs". [PDF]
europepmc +1 more source

