Results 71 to 80 of about 8,160,938 (248)

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Beyond Secondary Structure: Primary-Sequence Determinants License Pri-miRNA Hairpins for Processing [PDF]

, 2013
Vincent C. Auyeung, Igor Ulitsky, Sean E. McGeary, David P. Bartel   +3 more
openalex   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

FEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia, Eric Catalina‐Hernandez, Maialen Cabrerizo‐Idiazabal, Ramon Barnadas‐Rodríguez, Mario Lopez‐Martin, Alex Peralvarez‐Marin   +5 more
wiley   +1 more source

Internet Communication Disorder and the structure of the human brain: initial insights on WeChat addiction [PDF]

, 2018
Christian Montag, Zhiying Zhao, Cornelia Sindermann, Lei Xu, Meina Fu, Jia‐Lin Li, Xiaoxiao Zheng, Keshuang Li, Keith M. Kendrick, Jing Dai, Benjamin Becker   +10 more
openalex   +1 more source

Mesoscopic structure of mixed type domain walls in multiaxial ferroelectrics [PDF]

, 2020
Morozovska, Anna N., Eliseev, Eugene A., Fomichov, Yevhen M., Kalinin, Sergei V.   +3 more
openalex   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

FEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer, Matheus Felipe Santos, Maurício Mazzine Filho, Gabriela Oliveira Castro, Agustín Hernández, Manoel Aparecido Peres, Alejandro Miguel Katzin, Marcell Crispim   +7 more
wiley   +1 more source

One-dimensional twisted and tubular structures of zinc oxide by semiconductor-catalyzed vapor–liquid–solid synthesis [PDF]

, 2020
Pham, Thang, Kommandur Sampath, Lee Haeyeon, Zakharov, Dmitri, Filler, Michael A., Ross, Frances M.   +5 more
openalex   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

FEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur, Brian Acquaviva, Baylee A. Smith, Nathan Walker, Isabella Walter, Matthew L. Wohlever   +5 more
wiley   +1 more source

Design and Experimental Verification on Characteristics of Valve-Less Piezoelectric Pump Effected by Valve Hole Spacing

IEEE Access, 2019
Valve-less piezoelectric pumps possess the advantages of simple structure and absence of electromagnetic interference, which has accordingly drawn widespread attention. In this paper, in order to improve the performance of valve-less piezoelectric pumps,
Jiajian Ji, Song Chen, Xinyi Xie, Xiaoming Wang, Junwu Kan, Zhonghua Zhang, Jianping Li   +6 more
doaj   +1 more source

The Transformation of Galaxies within the Large-Scale Structure around a [CLC][ITAL]z[/ITAL][/CLC] = 0.41 Cluster [PDF]

, 2001
Tadayuki Kodama, Ian Smail, F. Nakata, Okamura S, R. G. Bower, Tadayuki Kodama, Ian Smail, F. Nakata, Okamura S, R. G. Bower   +9 more
openalex   +1 more source