Results 171 to 180 of about 5,072,023 (302)

The Antibacterial Type VII Secretion System of Bacillus subtilis: Structure and Interactions of the Pseudokinase YukC/EssB. [PDF]

mBio, 2022
Tassinari M, Doan T, Bellinzoni M, Chabalier M, Ben-Assaya M, Martinez M, Gaday Q, Alzari PM, Cascales E, Fronzes R, Gubellini F.   +10 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

Social Structure and Interactions Differentially Shape Aerotolerant and Anaerobic Gut Microbiomes in a Cooperative Breeding Species. [PDF]

Mol Ecol
Lee CZ, Worsley SF, Burke T, Komdeur J, Hildebrand F, Dugdale HL, Richardson DS.   +6 more
europepmc   +1 more source

Process-Structure-Formulation Interactions for Enhanced Sodium Ion Battery Development: A Review. [PDF]

Chemphyschem, 2022
Sawhney MA, Wahid M, Muhkerjee S, Griffin R, Roberts A, Ogale S, Baker J.   +6 more
europepmc   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

Study of the inhibition mechanism of HIV-1 integrase by diketoacids molecules

Journal of Virus Eradication, 2016
Léa El Khoury, Zeina Hobaika, Krystel El Hage, Serge Fermandjian, Jean-Philip Piquemal, Nohad Gresh, Richard G. Maroun   +6 more
doaj   +1 more source

GPR17 in Glioblastoma: Structure, Ligand Interactions, and Therapeutic Targeting. [PDF]

ACS Omega
Satyanarayana R, Chaitanya SS, Suresh Kumar I, Thiyagarajan R, Chandrabose S, Abass KS, Konda Mani S, Thirunavukarasou A, Kandhavelu M.   +8 more
europepmc   +1 more source

New polymorphic phase of arachidic acid crystal: structure, intermolecular interactions, low-temperature stability and Raman spectroscopy combined with DFT calculations. [PDF]

RSC Adv, 2023
Cardoso LMB, de Oliveira Neto JG, Saraiva GD, Leite FF, Ayala AP, Dos Santos AO, de Sousa FF.   +6 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Nonlinear drivers and spatial heterogeneity of urban heat islands in lake-dense regions across ecological stress-structure-service interactions. [PDF]

Sci Rep
Xiong S, Yang F, Fan H.
europepmc   +1 more source