Results 171 to 180 of about 1,344,305 (317)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Structure and variation of the mitochondrial genome of fishes. [PDF]

open access: yesBMC Genomics, 2016
Satoh TP, Miya M, Mabuchi K, Nishida M.
europepmc   +1 more source

The Next Generation: Aspects of Grammatical Variation in the Speech of some London Preadolescents

open access: yes, 2007
PhDThis thesis is a sociolinguistic investigation into aspects of non-phonological variation in a group of preadolescents recorded in outer east London.
Levey, Stephen
core  

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Sentence Structure Variation

open access: yes, 2018
This exercise was designed to help students understand the importance of sentence structure variation. A model passage was used to dissect and evaluate sentence structure variety, and then students practiced this skill in their own writing.
Armstrong, Kacie
core  

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

open access: yesMolecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Insurer market structure and variation in commercial health care spending. [PDF]

open access: yesHealth Serv Res, 2014
McKellar MR   +5 more
europepmc   +1 more source

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