Results 101 to 110 of about 18,131,040 (297)
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
An improved powertrain attributes development process with the use of design structure matrix [PDF]
, 2004 Thesis (S.M.)--Massachusetts Institute of Technology, System Design & Management Program, 2004.Includes bibliographical references (p. 131).Automobiles are becoming increasingly complicated and are creating more of a challenge for the engineering teams ...
Rinkevich, Daniel J. (Daniel Joseph), 1960- +1 more
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Structure-Based Design of Novel Benzimidazole Derivatives as Pin1 Inhibitors
Molecules, 2019 Peptidyl-prolyl cis/trans isomerase Pin1 plays a key role in amplifying and translating multiple oncogenic signaling pathways during oncogenesis. The blockade of Pin1 provided a unique way of disrupting multiple oncogenic pathways and inducing apoptosis.
Shuxiang Wang +6 more
doaj +1 more source
FEBS Letters, EarlyView.We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Using the design structure matrix and systems thinking to develop a requirements driven automotive closures design process [PDF]
, 2008 Thesis (S.M.)--Massachusetts Institute of Technology, System Design and Management Program, February 2008.Includes bibliographical references (p. 93).Thesis Outline and Flow: Chapter 1.
Corby, Robert J
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From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Optimal design of a composite wing structure for a flying-wing aircraft subject to multi-constraint [PDF]
, 2012 This thesis presents a research project and results of design and optimization of a composite wing structure for a large aircraft in flying wing configuration.
Xu, Rongxin.
core +3 more sources
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Rendering soil care across hotel, retailer, and farm with a mutuality service blueprint [PDF]
Design Research Society (DRS) conference, Boston, MA (USA), June 23rd-28th, 2024202406 bcchVersion of RecordOthersZero Foodprint ...
Wernli, M +3 more
core +1 more source
Molecules, 2019 To discover new antiproliferative agents with high efficacy and selectivity, a new series of 1-aryl-3-{4-[(pyridin-2-ylmethyl)thio]phenyl}urea derivatives (7a–7t) were designed, synthesized and evaluated for their antiproliferative activity against A549,
Chuanming Zhang +8 more
doaj +1 more source