Results 141 to 150 of about 18,131,040 (297)

Conceptual Frameworks and Practice on Nano-Micro Pore Structure Design of Bio-Aerogels. [PDF]

Gels
Yuan S, Yang J, Wu K, Qian H, Chen X, Kuang Y, Jiang F, Yang G, Zhu F, Riffat S.   +9 more
europepmc   +1 more source

Study on Seismic structural design in building structure design

Seismic structural design plays a crucial role in the field of architecture. It can not only effectively improve the seismic performance of buildings, reduce the losses caused by earthquake disasters, but also protect people's lives and property safety.
openaire   +2 more sources

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

A Bioinspired Soft Manipulator Based on Wave Spring Structure: Design and Control. [PDF]

Biomimetics (Basel)
Sui D, Zhang Z, Wang T, Zhao S, Zhang Y, Wang X.   +5 more
europepmc   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

Multifunctional Hydrogels in Sustainable Agriculture: Structure Design, Application and Future Challenges. [PDF]

Gels
Huang H, Wang L, Xue X, Yin M, Wang L, Dong Y, Xiao F, Chen X, Li C, Guo X, Wang X, Zhang L.   +11 more
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Diffusion-Based Protein Structure Design: Geometric Modelling, Validation Strategies, and Thermodynamic Challenges. [PDF]

Int J Mol Sci
Li W, Cadet X, Medina-Ortiz D, Davari MD, Sowdhamini R, Bessafi M, Damour C, Li Y, Miranville A, de Brevern AG, Cadet F.   +10 more
europepmc   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

A study protocol for mixed-methods evaluation of the structure, design, and availability of medical student wellbeing programs. [PDF]

PLoS One
Godbole N, Choi S, Shim K, Liu Y, Hu J, Wong J, Nguyen P, Chan SWC, Doan L, Lin N, Salcedo V, Yi SS.   +11 more
europepmc   +1 more source