Results 171 to 180 of about 18,131,040 (297)

Optimization of Insulation Structure Design for Enameled Wires Based on Molecular Structure Design. [PDF]

Polymers (Basel)
Yu Y, Li S, Weng L, Zhang X, Liu L, Chen Q.   +5 more
europepmc   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Mindfulness and resource-sensitive design : a literature overview and an agenda for research

21st International Conference on Engineering Design (ICED 17), Vancouver, Canada, 21-25 August 2017202403 bckwVersion of RecordSelf-fundedPublishedVoR ...
de Bont, C, Chan, WMH
core  

Transition graphs of interacting hysterons: structure, design, organization and statistics. [PDF]

R Soc Open Sci
Teunisse M, van Hecke M.
europepmc   +1 more source

Fitness functions for RNA structure design. [PDF]

Nucleic Acids Res, 2023
Ward M, Courtney E, Rivas E.
europepmc   +1 more source

Structural Design Vol ii Design of Simple Structures [PDF]

Nature, 1916
openaire   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Structure Design and Performance Study of Bionic Electronic Nasal Cavity. [PDF]

Biomimetics (Basel)
Chen P, Yin Z, Xu S, Wang P, Yang L, Lv Y.   +5 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

Augmenting the catalytic activity of ADzymes: strategic engineering from atomic structure design to macro-environmental interaction for enhanced biomedical efficacy. [PDF]

J Nanobiotechnology
Yu L, Gao F, Li C, Wu Y, Meng J, Yao Y, Wang S, Wang Y, Sun Z, Wang C, Jiang Y.   +10 more
europepmc   +1 more source