Results 201 to 210 of about 7,102,543 (272)

Heterogeneous Frustrated Lewis Pair Catalysts: Rational Structure Design and Mechanistic Elucidation Based on Intrinsic Properties of Supports. [PDF]

Acc Chem Res
Li J, Li G, Tsang SCE.
europepmc   +1 more source

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Scalable Synthesis of the Key Fexuprazan Intermediate and Investigation of a Reaction Mechanism

ACS Omega
Ting Wang, Yueting Hua, Fangbo Deng, Rui Wen, Haoyu Zhang, Chunshi Li, Yang Liu, Maosheng Cheng   +7 more
doaj   +1 more source

Guide RNA structure design enables combinatorial CRISPRa programs for biosynthetic profiling. [PDF]

Nat Commun
Fontana J, Sparkman-Yager D, Faulkner I, Cardiff R, Kiattisewee C, Walls A, Primo TG, Kinnunen PC, Garcia Martin H, Zalatan JG, Carothers JM.   +10 more
europepmc   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Two-Dimensional DOA Estimation for Coprime Planar Arrays: From Array Structure Design to Dimensionality-Reduction Root MUSIC Algorithm. [PDF]

Sensors (Basel)
Shi Y, Zhang X, Han S.
europepmc   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Adaptive Frame Structure Design for Sensing-Assisted Downlink Communication in the Vehicle-to-Infrastructure Scenario. [PDF]

Sensors (Basel)
Yao J, Wang Z, Zhang C, Hui H.
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Wall panel structure design optimization of a hexagonal satellite. [PDF]

Heliyon
Reda R, Ahmed Y, Magdy I, Nabil H, Khamis M, Lila MA, Refaey A, Eldabaa N, Elmagd MA, Ragab AE, Elsayed A.   +10 more
europepmc   +1 more source