Results 51 to 60 of about 7,102,543 (272)

Synthesis and Smo Activity of Some Novel Benzamide Derivatives

open access: yesMolecules, 2017
Two series of benzamides compounds bearing piperidine groups were synthesized and the Gli-luc luciferase activity was screened by Gys-luc luciferase gene detection method. Compound 5q showed promising inhibition of hedgehog (Hh) signaling pathway.
Huaiwei Ding   +8 more
doaj   +1 more source

Experimental verification of the key properties of a three-dimensional isotropic transmission line based superlens

open access: yes, 2006
Design and experimental realization of a three-dimensional superlens based on LC-loaded transmission lines are presented. Commercially available components and materials are used in the design.
Alitalo, Pekka   +2 more
core   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed   +5 more
wiley   +1 more source

Digital interchangeability design of aircraft control surfaces

open access: yesHangkong gongcheng jinzhan
With the gradual maturity and application of digital assembly technology,the interchangeability design adapting to digital quantity transfer is of significant practical significance for improving the efficiency of aircraft control surface design ...
LI Yunpeng, YAO Xionghua, GAO Shuai
doaj   +1 more source

Radiotherapy Delivery in Deep Inspiration for Pediatric Patients—Final Results of the Phase II Feasibility Study TEDDI

open access: yesPediatric Blood &Cancer, EarlyView.
Abstract Introduction The TEDDI trial tested the feasibility and reproducibility of deep‐inspiration breath‐hold (DIBH) in pediatric patients referred for radiotherapy. This report presents final results, including patient‐reported outcomes (PRO) and dosimetric comparison of DIBH and free‐breathing (FB).
Daniella Elisabet Østergaard   +11 more
wiley   +1 more source

Drilling system design project 1967: final report of frame design committee [PDF]

open access: yes, 1967
This report outlines the recommendations of the Frame Design Committee for the final design of the machine, each major part of the structure being considered individually in the following sections : 1. Worktables 2. Guide and Slideways 3.
Morrison, W., Sutcliffe, R. S.
core  

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura   +5 more
wiley   +1 more source

Design, Synthesis and Bioactivity Evaluation of 4,6-Disubstituted Pyrido[3,2-d]pyrimidine Derivatives as Mnk and HDAC Inhibitors

open access: yesMolecules, 2020
Both HDACs and Mnks play important role in translating multiple oncogenic signaling pathways during oncogenesis. As HDAC and Mnk are highly expressed in a variety of tumors; thus simultaneous inhibit HDAC and Mnk can increase the inhibition of tumor cell
Kun Xing   +5 more
doaj   +1 more source

Dispersion Analysis of the Testing Method for the Flexural Performance of Honeycomb Sandwich Structure

open access: yesHangkong gongcheng jinzhan, 2022
In the test of the flexural performance of the honeycomb sandwich structure,due to the different test methods,there is a situation that the data dispersion is large,which causes the reliability to be reduced,which is not conducive to the evaluation of ...
LI Yunpeng, GUO Xiang
doaj   +1 more source

Combinatorial RNA Design Designability and Structure-Approximating Algorithm in Watson-Crick and Nussinov-Jacobson Energy Models [PDF]

open access: yes, 2016
We consider the Combinatorial RNA Design problem, a minimal instance of RNA design where one must produce an RNA sequence that adopts a given secondary structure as its minimal free-energy structure.
Haleš, Jozef   +4 more
core   +5 more sources

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