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This chapter is part of the book "Introduction to Protein Structural Bioinformatics".
Mouhib, Halima +6 more
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Although experimental protein-structure determination usually targets known proteins, chains of unknown sequence are often encountered. They can be purified from natural sources, appear as an unexpected fragment of a well characterized protein or appear ...
Grzegorz Chojnowski +6 more
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Poly(ADP-ribose) polymerase 1 (PARP-1), an enzyme that modifies nuclear proteins by poly(ADP-ribosyl)ation, regulates various cellular activities and restricts the lytic replication of oncogenic gammaherpesviruses by inhibiting the function of ...
Woo-Chang Chung +7 more
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Time-resolved crystallography of biomolecules in action has advanced rapidly as methods for serial crystallography have improved, but the large number of crystals and the complex experimental infrastructure that are required remain serious obstacles to ...
Jonathan A. Clinger +4 more
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The phenyl vinyl ether–methanol complex: a model system for quantum chemistry benchmarking
The structure of the isolated aggregate of phenyl vinyl ether and methanol is studied by combining a multi-spectroscopic approach and quantum-chemical calculations in order to investigate the delicate interplay of noncovalent interactions.
Dominic Bernhard +9 more
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Application of GISAXS in the Investigation of Three-Dimensional Lattices of Nanostructures
The application of the grazing-incidence small-angle X-ray scattering (GISAXS) technique for the investigation of three-dimensional lattices of nanostructures is demonstrated.
Lovro Basioli +5 more
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Structural Essentialism and Determinism
The paper tries to develop Bartels’s modern essentialism as a structural-role theory of identity for spacetime points. I adopt Hoefer’s idea of denying primitive identity for this theory and apply it to GTR and prerelativistic physics to find different versions of essentialism and different definitions of determinism which are coherent with them.
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A Brief Study of Mass Spectrometry of Natural Products
The physical and chemical data of the pure substance can be analysed to determine the structure. In the current era of structural elucidation, NMR spectroscopy and mass spectroscopy, especially the various types of 2D NMR, are used extensively, while ...
Insha Ur Rehman +3 more
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Exploiting prior knowledge about biological macromolecules in cryo-EM structure determination
Three-dimensional reconstruction of the electron-scattering potential of biological macromolecules from electron cryo-microscopy (cryo-EM) projection images is an ill-posed problem.
Dari Kimanius +7 more
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Conservation of the structure and function of bacterial tryptophan synthases
Tryptophan biosynthesis is one of the most characterized processes in bacteria, in which the enzymes from Salmonella typhimurium and Escherichia coli serve as model systems.
Karolina Michalska +15 more
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