Results 1 to 10 of about 8,136,725 (292)

Protein contact network explorer: topological analysis of protein structures [PDF]

Frontiers in Bioinformatics
IntroductionThe functions of proteins are primarily governed by coordinated interactions among amino acid residues throughout their three-dimensional structures.
Akhurath Ganapathy, Sanjana Vijay Krishnan, Arnold Emerson Isaac   +2 more
doaj   +2 more sources

findMySequence: a neural-network-based approach for identification of unknown proteins in X-ray crystallography and cryo-EM

IUCrJ, 2022
Although experimental protein-structure determination usually targets known proteins, chains of unknown sequence are often encountered. They can be purified from natural sources, appear as an unexpected fragment of a well characterized protein or appear ...
Grzegorz Chojnowski, Adam J. Simpkin, Diego A. Leonardo, Wolfram Seifert-Davila, Dan E. Vivas-Ruiz, Ronan M. Keegan, Daniel J. Rigden   +6 more
doaj   +1 more source

¹⁷O NMR Spectroscopy: A Novel Probe for Characterizing Protein Structure and Folding

Biology, 2021
Oxygen is a key atom that maintains biomolecular structures, regulates various physiological processes, and mediates various biomolecular interactions. Oxygen-17 (17O), therefore, has been proposed as a useful probe that can provide detailed information ...
Srinivasan Muniyappan, Yuxi Lin, Young-Ho Lee, Jin Hae Kim   +3 more
doaj   +1 more source

Capturing structural changes of the S1 to S2 transition of photosystem II using time-resolved serial femtosecond crystallography

IUCrJ, 2021
Photosystem II (PSII) catalyzes light-induced water oxidation through an Si-state cycle, leading to the generation of di-oxygen, protons and electrons.
Hongjie Li, Yoshiki Nakajima, Takashi Nomura, Michihiro Sugahara, Shinichiro Yonekura, Siu Kit Chan, Takanori Nakane, Takahiro Yamane, Yasufumi Umena, Mamoru Suzuki, Tetsuya Masuda, Taiki Motomura, Hisashi Naitow, Yoshinori Matsuura, Tetsunari Kimura, Kensuke Tono, Shigeki Owada, Yasumasa Joti, Rie Tanaka, Eriko Nango, Fusamichi Akita, Minoru Kubo, So Iwata, Jian-Ren Shen, Michihiro Suga   +24 more
doaj   +1 more source

Dihedral Angle Measurements for Structure Determination by Biomolecular Solid-State NMR Spectroscopy

Frontiers in Molecular Biosciences, 2021
In structural studies of immobilized, aggregated and self-assembled biomolecules, solid-state NMR (ssNMR) spectroscopy can provide valuable high-resolution structural information.
Patrick C. A. van der Wel
doaj   +1 more source

Rapid and efficient room-temperature serial synchrotron crystallography using the CFEL TapeDrive

IUCrJ, 2022
Serial crystallography at conventional synchrotron light sources (SSX) offers the possibility to routinely collect data at room temperature using micrometre-sized crystals of biological macromolecules.
Kara A Zielinski, Andreas Prester, Hina Andaleeb, Soi Bui, Oleksandr Yefanov, Lucrezia Catapano, Alessandra Henkel, Max O. Wiedorn, Olga Lorbeer, Eva Crosas, Jan Meyer, Valerio Mariani, Martin Domaracky, Thomas A. White, Holger Fleckenstein, Iosifina Sarrou, Nadine Werner, Christian Betzel, Holger Rohde, Martin Aepfelbacher, Henry N. Chapman, Markus Perbandt, Roberto A. Steiner, Dominik Oberthuer   +23 more
doaj   +1 more source

Evaluation of Transmembrane Protein Structural Models Using HPMScore

BioMedInformatics, 2023
Transmembrane proteins (TMPs) are a class of essential proteins for biological and therapeutic purposes. Despite an increasing number of structures, the gap with the number of available sequences remains impressive.
Stéphane Téletchéa, Jérémy Esque, Aurélie Urbain, Catherine Etchebest, Alexandre G. de Brevern   +4 more
doaj   +1 more source

AlphaFold2 Update and Perspectives

BioMedInformatics, 2023
Access to the three-dimensional (3D) structural information of macromolecules is of major interest in both fundamental and applied research. Obtaining this experimental data can be complex, time consuming, and costly.
Sébastien Tourlet, Ragousandirane Radjasandirane, Julien Diharce, Alexandre G. de Brevern   +3 more
doaj   +1 more source

Development of serial X-ray fluorescence holography for radiation-sensitive protein crystals

Journal of Synchrotron Radiation, 2023
X-ray fluorescence holography (XFH) is a powerful atomic resolution technique capable of directly imaging the local atomic structure around atoms of a target element within a material.
Artoni Kevin R. Ang, Yasufumi Umena, Ayana Sato-Tomita, Naoya Shibayama, Naohisa Happo, Riho Marumi, Yuta Yamamoto, Koji Kimura, Naomi Kawamura, Yu Takano, Tomohiro Matsushita, Yuji C. Sasaki, Jian-Ren Shen, Kouichi Hayashi   +13 more
doaj   +1 more source

Microfluidic devices for protein analysis using intact and top‐down mass spectrometry

View, 2023
Top‐down mass spectrometry (TD‐MS) provides unique information on compositions, structures, and functions of proteins or protein complexes and has been recognized as a powerful approach to complement conventional tools in protein analysis.
Xinyang Shao, Yanyi Huang, Guanbo Wang
doaj   +1 more source