Results 161 to 170 of about 306,884 (301)

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

FEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin, Ziyang Yuan, Wenli Jiang, Ai Guo   +3 more
wiley   +1 more source

Microbial dl-Peptidases Enable Predator Defense and Facilitate Structure Elucidation of Complex Natural Products. [PDF]

J Am Chem Soc
Zhang S, Huang Y, Schlabach K, Tran MA, Nachawati R, Bader N, Komor AJ, Hertweck C, Schindelin H, Lakemeyer M, Hellmich UA, Stallforth P.   +11 more
europepmc   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

Structural Elucidation of Destruxin A [PDF]

Agricultural and Biological Chemistry, 1966
Akinori Suzuki, Shimpei Kuyama, Yoshinori Kdaira, Saburo Tamura   +3 more
openaire   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

Further Insights Into the Metabolism of LGD-4033 in Human Urine. Part 1. Structure Elucidation of Additional Important Metabolites. [PDF]

Drug Test Anal
Angelis YS, Sakellariou P, Thevis M, Thomas A, Petrou M, Pitsinos EN.   +5 more
europepmc   +1 more source

Molecular Structure of Endotoxins from Gram-negative Marine Bacteria: An Update (review) [PDF]

, 2007
A. Molinaro, E. L. Nazarenko, LANZETTA, ROSA, LEONE, SERENA, M. Parrilli, SILIPO, ALBA   +5 more
core   +1 more source

Emerging insights into CC and CXC chemokines and their receptors in Mycobacterium tuberculosis infection

FEBS Open Bio, EarlyView.
The dual roles of CC and CXC chemokines in distinguishing active, latent, and subclinical tuberculosis were reviewed, along with an evaluation of their potential as diagnostic biomarkers and therapeutic targets to advance precision medicine in tuberculosis management. The graphical abstract was generated with AI assistance (Gemini 3.0).
Xuying Yin, Dangsheng Xiao, Jiezuan Yang
wiley   +1 more source

Structure elucidation and evaluation of the antimicrobial and antitumor activities of 5-methylthiazole-based Schiff base and its metal chelates. [PDF]

Sci Rep
Wahdan KM, Mandour HSA, El-Ghamry HA, El-Gamil MM, Khedr AM.   +4 more
europepmc   +1 more source

Special Issue-"Isolation, Structure Elucidation and Biological Activity of Natural Products". [PDF]

Molecules, 2023
Takahashi JA.
europepmc   +1 more source