Results 301 to 310 of about 314,098 (329)

Modern NMR techniques for structure elucidation

Magnetic Resonance in Chemistry, 1986
AbstractThe rapid growth during the last decade of multiple pulse methods in one (1D) and two‐dimensional (2D) NMR has produced over 100 new techniques of potential use in high‐resolution NMR. This review sets out to identify and to illustrate those new methods which are most useful in the determination of molecular structure.
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Elucidating pathological fibril structure

Science, 2017
Structural Biology Amyloid-β (Aβ) is a key pathological contributor to Alzheimer's disease. Gremer et al. used cryoelectron microscopy data to build a high-quality de novo atomic model of Aβ fibrils (see the Perspective by Pospich and Raunser). The complete structure reveals all 42 amino acids (including the entire N terminus) and provides a structural
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Challenging Structure Elucidator

2011
This chapter will review examples of challenges solved using StrucEluc and will demonstrate all of the diverse approaches for computer assisted structure elucidation discussed in this volume. The examples will include (1) the elucidation of a family of complex alkaloid natural product structures (2) the elucidation of unexpected reaction products in a ...
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Elucidating the Structure of Poly(dopamine)

Langmuir, 2012
Herein we propose a new structure for poly(dopamine), a synthetic eumelanin that has found broad utility as an antifouling agent. Commercially available 3-hydroxytyramine hydrochloride (dopamine HCl) was polymerized under aerobic, aqueous conditions using tris(hydroxymethyl)aminomethane (TRIS) as a basic polymerization initiator, affording a darkly ...
Dreyer, Daniel R., Miller, Daniel J., Freeman, Benny D., Paul, Donald R., Bielawski, Christopher W.   +4 more
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Researchers elucidate colibactin structure

C&EN Global Enterprise, 2019
Some Escherichia coli bacteria in the gut produce a family of metabolites called colibactins, which are associated with increased risk of colon cancer in people.
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Strategies of Structure Elucidation

2015
Different strategies regarding the application of the system depending on the specific features of the problem under analysis are discussed in this chapter. The input of 1D and 2D NMR spectroscopy data (automated and manual) to the program and the creation of electronic data tables are outlined.
Mikhail E. Elyashberg, Antony J. Williams   +1 more
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Computer assisted structure elucidation

Analytica Chimica Acta, 1987
Neil A.B. Gray, Albert Platt
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Structural elucidation of saponins

1995
Publisher Summary Saponins constitute an important class of secondary metabolites from plant and animal domains. They display a broad spectrum of biological activities that have raised the interest of phytochemists for the past 40 years. With molecular weights ranging from 600 to 2000 daltons, their structures are complex.
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Structure Elucidation Using Strict Structure Generation

2015
Part III is divided into two chapters—Chaps. 4 and 5. These chapters are the most important for those who want to become proficient in the routine application of CASE analysis for solving structural problems which appear in analytical laboratories. Here CASE-based solutions to 66 real-world structural problems are fully explained.
Mikhail E. Elyashberg, Antony J. Williams   +1 more
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[Structure elucidation of gestodene].

Arzneimittel-Forschung, 1986
The structure of 17 alpha-ethinyl-17 beta-hydroxy-18-methyl-4,15-estradien-3-one (gestodene) was elucidated by the spectrometric methods UV, IR, NMR, MS.
G, Cleve, E, Frost, G A, Hoyer, D, Rosenberg, A, Seeger   +4 more
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