Results 51 to 60 of about 311,932 (330)

Molecular bases of circadian magnesium rhythms across eukaryotes

open access: yesFEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Shotgun ion mobility mass spectrometry sequencing of heparan sulfate saccharides [PDF]

open access: yes, 2020
Despite evident regulatory roles of heparan sulfate (HS) saccharides in numerous biological processes, definitive information on the bioactive sequences of these polymers is lacking, with only a handful of natural structures sequenced to date.
Grabarics, Márkó   +9 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

open access: yesFEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang   +8 more
wiley   +1 more source

Synthesis and Structure Elucidation of N′-(4-Methoxybenzylidene)-5-methyl-1-phenyl-1H-1,2,3-triazole-4-carbohydrazide

open access: yesMolbank, 2018
N′-(4-Methoxybenzylidene)-5-methyl-1-phenyl-1H-1,2,3-triazole-4-carbohydrazide (3) was synthesized in a yield of 88% from an acid-catalyzed reaction of 5-methyl-1-phenyl-1H-1,2,3- triazole-4-carbohydrazide and 4-methoxybenzaldehyde in ethanol under
Mohammad Hayal Alotaibi   +5 more
doaj   +1 more source

Modal Considerations on Information Processing and Computation in the Nervous System [PDF]

open access: yes, 2013
We can characterize computationalism very generally as a complex thesis with two main parts: the thesis that the brain (or the nervous system) is a computational system and the thesis that neural computation explains cognition.
Wajnerman Paz, Abel
core   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

BALANOCARPOL AND HEIMIOL A, TWO RESVERATROLS DIMER FROM STEM BARK Hopea mengarawan (Dipterocarpaceae)

open access: yesIndonesian Journal of Chemistry, 2010
Isolation and structure elucidation of two resveratrols dimer, namely balanocarpol (1) and heimiol A (2) from stem bark of Hopea mengarawan had been done.
Sri Atun   +3 more
doaj   +1 more source

Synthesis, structural characterization and myorelaxant activity of 4-naphthylhexahydroquinoline derivatives containing different ester groups [PDF]

open access: yesJournal of the Serbian Chemical Society, 2016
The present study reports the synthesis, structural characterization and myorelaxant activity evaluation of a series of 16 novel 4-naphthyl-hexahydroquinoline derivatives.
Gündüz Miyase Gözde   +9 more
doaj   +1 more source

Structure elucidation, biosynthesis, total synthesis and antibacterial in-vivo efficacy of myxobacterial Corramycin [PDF]

open access: gold, 2022
Cédric Couturier   +32 more
openalex   +1 more source

Structure elucidation of sildenafil analogues in herbal products. [PDF]

open access: yes, 2004
The structure of unknown compounds present in herbal products was elucidated using liquid chromatography-electrospray ionization-mass spectrometry, direct-infusion electrospray ionization-mass spectrometry, and nuclear magnetic resonance.
Bakker, F   +7 more
core   +1 more source

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