Results 111 to 120 of about 1,722,715 (334)

Structured light interferometry

open access: yes, 2019
Optical interferometry has made tremendous development in fundamentals and applications of light. Traditional optical interferometry using simplex plane phase light just allows one dimensional measurement, but incapable of retrieving multidimensional movement. Here, we present new structured light interferometry to achieve simultaneous determination of
Fang, Liang, Wan, Zhenyu, Wang, Jian
openaire   +2 more sources

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

The longitudinal dynamics evolution of optical skyrmions via meta-optics

open access: yesNanophotonics
Skyrmions, as topologically structured light fields, have attracted considerable attention due to their unique topological properties and potential applications such as optical communication and advanced sensing technologies.
He Tiantian   +6 more
doaj   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

open access: yesMolecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller   +17 more
wiley   +1 more source

Fast 3D Reconstruction using Structured Light Methods [PDF]

open access: yes
In this presentation we discuss the use of structured light scanners for the general problem of 3D surface reconstruction. We show that projecting patterns of light provide an inexpensive means of consistent 3D scanning at high resolution, in real-time ...
Rodrigues, Marcos
core  

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola   +12 more
wiley   +1 more source

Interaction Between Atoms and Structured Light Fields

open access: yesAtoms
Structured light encompasses a vast variety of light fields. It has unique properties such as non-uniform transverse intensity and a polarization pattern across their beam cross-sections.
Shreyas Ramakrishna, Stephan Fritzsche
doaj   +1 more source

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