Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard +12 more
wiley +1 more source
Validation of Consumer-Grade 3D Scanners for Clinical Facial Reconstruction: Comparison with a Professional Structured-Light Reference System. [PDF]
Ondrejová B +5 more
europepmc +1 more source
Enzyme therapy in a structural light
The paper by Gilski et al. in this issue [IUCrJ (2026), 13, 132-145] focuses on the stereochemical analysis of the catalytic mechanism of asparaginases with the aim of resolving key ambiguities in the mechanism. These enzymes have found truly remarkable therapeutic success in the treatment of childhood leukemias.
openaire +3 more sources
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill +6 more
wiley +1 more source
Portable structured-light 3D volumetry for breast and flap assessment: Technical validation and workflow development. [PDF]
Chen Y +9 more
europepmc +1 more source
Digital Structures and Light Movements [PDF]
Esther Rolinson, Sean M. Clark
openaire +2 more sources
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Structured Light Camera's Point Clouds Captured and Stitched by Humanoid for 3D Objects Based on ICP Registration Algorithm. [PDF]
Lin HY, Hung CP, Tu KY, Kuo FT.
europepmc +1 more source
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Phase-Domain Peak-Based Correspondence Extraction for Robust Structured-Light Imaging. [PDF]
Ćurković A, Ćurković M, Grebo A.
europepmc +1 more source

