Results 41 to 50 of about 6,709,288 (231)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Singular Higher-Order Complete Vector Bases for Finite Methods [PDF]

, 2004
This paper presents new singular curl- and divergence- conforming vector bases that incorporate the edge conditions. Singular bases complete to arbitrarily high order are described in a unified and consistent manner for curved triangular and ...
Graglia, Roberto, Lombardi, Guido
core   +1 more source

Between earth and sky. War architecture in Sardinia: a landscape to preserve

ArcHistoR Architettura Storia Restauro: Architecture History Restoration, 2019
In the first years of the Second World War along the coast of Sardinia, a system of military defenses was built consisting essentially of bunkers and concrete batteries, many of which are still standing, as "testarde rovine" that resist the passage of ...
Andrea Pirinu, Andres Martinez-Medina
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells

FEBS Open Bio, EarlyView.
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour, Christine Volmert, Valentina Piano   +2 more
wiley   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Analytical new soliton solutions and stability analysis of the (2 + 1)-dimensional time-fractional nonlinear GZKBBM equation

Partial Differential Equations in Applied Mathematics
In this study, we investigate the soliton solutions of the (2 + 1)-dimensional time-fractional nonlinear generalized Zakharov-Kuznetsov-Benjamin-Bona-Mahony equation using the extended sinh-Gordon expansion approach.
Nazia Parvin, Hasibun Naher, M. Ali Akbar   +2 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Model Reduction of LPV Control with Bounded Parameter Variation Rates [PDF]

, 2006
This paper proposes a reduced-order controller of linear parameter varying systems. The parameters are available for measurement while their ranges and rates of variation are assumed to be bounded.
Riyanto, T. Bambang, Widowati, Widowati
core   +1 more source