Results 41 to 50 of about 287,902 (268)

Isotropically Random Orthogonal Matrices: Performance of LASSO and Minimum Conic Singular Values

, 2015
Recently, the precise performance of the Generalized LASSO algorithm for recovering structured signals from compressed noisy measurements, obtained via i.i.d. Gaussian matrices, has been characterized.
Hassibi, Babak, Thrampoulidis, Christos
core   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

Computing Lower Bounds of µ-Values for a Class of Rotary Electrical Machines

International Journal of Analysis and Applications, 2019
In this article we present the computations of lower bounds of well-known mathematical quantity in control theory known as structured singular value for a family of structured matrices obtained for a DC Motor, that is an electrical machine.
Mutti-Ur Rehman, M. Fazeel Anwar
doaj   +2 more sources

Analysis of feedback systems with structured uncertainties [PDF]

, 1982
The paper introduces a general approach for analysing linear systems with structured uncertainty based on a new generalised spectral theory for matrices.
Doyle, John
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Matrix Nearness Problems, D-Stability and μ-Values in Economic Models

IEEE Access
In this paper, we investigate the interconnection between $D$ -stability and the structured singular value ( $\mu $ -values) to analyze linear time invariant dynamical systems subject to structured uncertainties.
Mutti-Ur Rehman, Saima Akram, Ali Algefary   +2 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

A μ-Synthesis Framework for Multi-Domain Robust Load Frequency Control Under Concurrent Communication Delays and Parametric Uncertainties

IEEE Access
The integration of communication networks into modern power systems introduces variable time delays that degrade the performance of traditional Load Frequency Control (LFC), while the shift towards renewable energy sources increases system vulnerability ...
Chadi Nohra, Bechara Nehme, Raymond Ghandour, Ossama Dankar, Mahmoud Khaled, Ahmed Mohsin Alsayah   +5 more
doaj   +1 more source