Results 41 to 50 of about 1,468 (231)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The validity of oral assessment (viva) that assesses specific and unique competencies in a post-graduate psychiatry examination

Sri Lanka Journal of Psychiatry, 2013
Background Studies have criticized oral assessments for having poor validity and reliability. There is limited research on structured oral assessments that assess specific competencies.
Varuni de Silva, Raveen Hanwella, Gominda Ponnamperuma   +2 more
doaj   +1 more source

Structured online vivas for evaluating professional competency in a capstone allied health course: A pilot study

Advancing Scholarship and Research in Higher Education, 2023
The aim of this pilot study was to develop structured online vivas as authentic assessments for capstone students enrolled in the medical sonography program in an Australian university. The objective was to evaluate the professional competency of trainee students who were transitioning to graduate as accredited sonographers.
Sandhya Maranna, Brooke Osborne, Shashi Nallaya   +2 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

STANDARDIZATION OF EVALUATION TOOL BY COMPARING SPOT, UNSTRUCTURED VIVA WITH OBJECTIVE STRUCTURED PRACTICAL EXAMINATION IN MICROANATOMY [PDF]

International Journal of Medical and Clinical Research, 2012
Evaluation of students is a vital component of any educational process and it is necessary to assess their performance. It also gets a feedback of teaching process so as to improve the performance of teacher and student both.
SABNIS AS, BHOSALE Y
openaire   +1 more source

Effectiveness of a blended viva format in cardiovascular physiology for first-year MBBS students: An initial report

Journal of Medical Education Development
Background & Objective: Oral examinations or viva is a common mode of assessment for medical students. It is not possible to cover the entire syllabus and students often feel that the “luck factor” plays a major role in deciding their performance ...
Krishnan Srinivasan, Sundareswaran Loganathan, Abhishek Sinha, Naveen Puttaraju, Anindita Mahanta, Manasi Bhattacharjee   +5 more
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Reliability of a viva assessment of clinical reasoning in an Australian pre-professional osteopathy program assessed using generalizability theory [PDF]

Journal of Educational Evaluation for Health Professions, 2017
Clinical reasoning is situation-dependent and case-specific; therefore, assessments incorporating different patient presentations are warranted. The present study aimed to determine the reliability of a multi-station case-based viva assessment of ...
Brett Vaughan, Paul Orrock, Sandra Grace
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source