Results 121 to 130 of about 441,298 (300)

[Struggling against poverty or its effects ? Early intervention programs.].

open access: yesSante mentale au Quebec, 2012
This article looks at poverty from the point of view that it does not necessarily correspond to the widespread image of chronic despair and resignation, acquired and transmitted from one generation to the next. The author argues such an image is produced by the fact that social and mental health services deal mainly with families at grips with multiple,
openaire   +1 more source

Citizenship and the Politics of Civic Driven Change [PDF]

open access: yes, 2012
Nation states are premised on the legitimizing presence of a polity comprised of citizens. The politics of this relationship is central to discourse on how societies evolve.
Alan Fowler, Kees Biekart
core  

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Barren Lands and Barren Bodies In Navajo Nation: Indian Women WARN about Uranium, Genetics, and Sterilization [PDF]

open access: yes, 2019
Founded by Native American women in 1974, Women of All Red Nations (WARN) insisted that the ongoing Indian public health crisis could not be properly understood exclusively within the context of the exploitation and pollution of the physical environment.
Bolton, Marie, Unger, Nancy C.
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

The Importance Of Zakat In Struggle Against Circle Of Poverty And Income Redistribution

open access: yes, 2015
{"references": ["B.S. Nursi, I\u015faratul Icaz, Istanbul, 2013.", "F.F. Senses, Kuresellesmenin Oteki Yuzu Yoksulluk, Istanbul, 2013, p.62.", "J. Drewnosky, \"Poverty: It is Meaning and Measurement\", Development\nand Change, 1997, Vol: 8, Issue 2, pp.183-208.", "E.
openaire   +1 more source

Power and the durability of poverty: a critical exploration of the links between culture, marginality and chronic poverty [PDF]

open access: yes, 2007
A   +187 more
core   +1 more source

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