Results 91 to 100 of about 5,991,366 (246)

Patient-centeredness and empathy in a bilingual interprofessional primary care teaching clinic: a pilot study

Journal of Multidisciplinary Healthcare, 2016
Sallie D Mayer,1 Erika Peterfy,2 Steven H Crossman,3 Lisa Burroughs Phipps,4 Allison A Vanderbilt5 1Bon Secours Virginia Health System, Bon Secours Medical Group, Midlothian, VA, 2School of Pharmacy, Virginia Commonwealth University, Charlotte, NC ...
Mayer SD, Peterfy E, Crossman SH, Phipps LB, Vanderbilt AA   +4 more
doaj  

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Delivery of Pediatric Student-Led Speech and Language Therapy Services at a University Rehabilitation Clinic in Cyprus: Children Accessing Services

Children
Background/Objectives: Early identification and intervention in speech and language therapy (SLT) are essential for children’s academic, social, and emotional development. In Cyprus, barriers such as long waiting lists, financial constraints, and limited
Theodora Papastefanou, Paris Binos, Despo Minaidou, Kakia Petinou, Costas A. Christophi, Eleni Theodorou   +5 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Street Law for Specific Communities: A Project for Persons with Disabilities

International Journal of Clinical Legal Education
This article will discuss the need for legal education programs for Persons with Disabilities, how an innovative Street Law Program was created, and the benefits of such a program.
Dema Lham, Thuji Wangmo, David W. Tushaus, Yeshey Dema   +3 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Student perspectives on student-led family medicine clinics in Qatar: a descriptive qualitative study

BMC Medical Education
Background Student-led clinic is an educational-professional training environment where students are leading the care of patients under the supervision of licensed health care professionals.
Suhad Daher-Nashif, Noora Ahmed A. M. Al-Mutawa, Mohammed Ali Kalathingal, Rahma Saad, Khalid Bashir   +4 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Sustaining Legal Clinics Through Summer: A Strategic Response to Rural Legal Advice Deserts in the Southwest of England

International Journal of Clinical Legal Education
This From the Field Report, based on a single clinic case study, advances the proposition that strategically placed drop-in clinics at the outset of the summer period can serve as an effective intervention to mitigate the operational challenges faced by
Kim McDonald
doaj   +1 more source