Advanced Science, EarlyView.This study demonstrates that somatic PIK3CA mutations suppress PPT1 expression via activation of the PI3K–AKT–c‐JUN axis. This reduction in PPT1 weakens its interaction with P300, thereby increasing palmitoylation at C1176 of P300 and protecting P300 from lysosomal degradation.
Hongrui Chen +7 more
wiley +1 more source
The Social Perception of Teachers' Emotional Intelligence and Problematic Internet Use among Spanish Adolescents: A Serial Mediation Model Involving Teacher-Student Relationships and Stress. [PDF]
Psychosoc IntervGómez-Hombrados J, Extremera N.
europepmc +1 more source
Dorsal Raphe VIP Neurons Are Critical for Survival‐Oriented Vigilance
Advanced Science, EarlyView.DRNVIP neurons in mice and primates are strategically positioned to influence the central extended amygdala via feedback loops. They regulate the excitability of PKC‐δ neurons in the ovBNST and CeA through glutamate release. Their ablation heightens activity in these regions, disrupts active‐phase sleep architecture, enhances risk assessment behaviors ...
Adriane Guillaumin +15 more
wiley +1 more source
The impact of emotional labor on the mental health of vocational college teachers in China: the mediating role of occupational identity and the moderating role of teacher-student relationships. [PDF]
BMC PsycholSui M, Zhou M, Yang Y.
europepmc +1 more source
Dual‐Strategy Design of Heterojunction‐Enhanced Piezoelectric Hydrogels for Periodontitis Treatment
Advanced Science, EarlyView.This study developed a piezoelectric hydrogel integrating heterojunction enhancement and dual‐salt synergy, combining robust electrical performance with mechanical stability and bioactivity to better match the periodontal microenvironment. Under ultrasound activation, the hydrogel markedly promotes macrophage M2 polarization, thereby reducing the ...
Qiangqiang Zhou +10 more
wiley +1 more source
Classroom climate dimensions, self-efficacy, and music aesthetic literacy: a mediation study with Chinese non-music major college students. [PDF]
Front PsycholZhao L, Huang W, Han B, Wu X.
europepmc +1 more source
Climate Change Agricultural Comparative Advantage and the US Trade Balance
Applied Economic Perspectives and Policy, EarlyView.ABSTRACT Current science indicates that warming and elevated atmospheric CO2 will have ambiguous results for crop productivity depending on crop type and geographic location, whereas increased heat stress makes livestock and human labor less productive.
Elizabeth A. Fraysse +2 more
wiley +1 more source
Educational anxiety triggered by artificial intelligence technology: pathways and configuration analysis affecting teachers' professional well-being. [PDF]
Front Public HealthWan Q, Zhang H, Cao J, Tao H.
europepmc +1 more source
Advanced Energy and Sustainability Research, EarlyView.This study introduces a temperature‐electric field synergy strategy to enhance lithium‐ion battery performance at low temperatures. It reveals interfacial mechanisms: low temperatures cause deterioration, while room temperature aids stable interphase formation.
Zhenqiang Guo +11 more
wiley +1 more source
A perplexing silence: unlocking student communication through teacher humor in the EFL classroom. [PDF]
Front PsycholZhou T, Chen S, Cao J.
europepmc +1 more source