Results 81 to 90 of about 1,279,057 (297)

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Student engagement with self-instructional course materials : a thesis presented in partial fulfilment of the requirements for the degree of Master of Education in Distance and On-line Learning at Massey University, Extramural, New Zealand [PDF]

open access: yes, 2010
This study is concerned with understanding how students engage with self-instructional materials on campus and at a distance within the context of the hybrid course offered at ABC College.
Cowie, Peter, Cowie, Peter
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Vigor, Dedication and Absorption: Work engagement among secondary school English teachers in Indonesia [PDF]

open access: yes, 2007
This paper investigates the work engagement among a sample of 152 secondary school English teachers in Yogyakarta, Indonesia, sampled from a competency-based integrated training course.
Basikin, Basikin
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The relationship between student engagement and dropout risk in early adolescence

open access: yesInternational Journal of Educational Research Open
One of the most reliable predictors of school effectiveness is student engagement, which is not only related to students’ current achievement but also long-term outcomes.
Lilla Szabó   +2 more
doaj   +1 more source

Critiques of Student Engagement

open access: yesHigher Education Policy, 2017
Student engagement initiatives at the national, institutional and classroom level have emerged against a backdrop of rising participation rates and the marketisation of higher education. This context has informed the development of a literature that is heavily influenced by cause-effect framing and a focus on effectiveness.
Macfarlane, Bruce, Tomlinson, Michael
openaire   +6 more sources

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

open access: yesFEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel   +13 more
wiley   +1 more source

Considering the Role of Tutoring in Student Engagement: Reflections from a South African University

open access: yesJournal of Student Affairs in Africa, 2017
Student engagement has been defined as the extent to which students are engaged in activities that higher education research has shown to be linked with high-quality learning outcomes.
Faroa Brendon Duran
doaj   +1 more source

Implementing Guided Inquiry Learning and Measuring Engagement Using an Electronic Health Record System in an Online Setting [PDF]

open access: yes, 2018
In many courses, practical hands-on experience is critical for knowledge construction. In the traditional lab setting, this construction is easy to observe through student engagement.
Maity, Pallavi   +2 more
core  

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