Results 111 to 120 of about 7,010,785 (247)

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

A Systematic Literature Review of Entrepreneurial Education in Electrical, Electronic, and Computer Engineering Curricula

open access: yesIEEE Access
This study contributes to entrepreneurship education within electrical, electronic and computer (EEC) engineering curricula by providing a comprehensive overview of the teaching methodologies and assessment designs currently employed by educators.
Jonathan W. Browning, John Bustard
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

open access: yesFEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis   +2 more
wiley   +1 more source

Enacting Transition Pedagogy at a School Level: An Action Research Analysis of Institutional Change Using Schein’s Model of Organisational Culture

open access: yesStudent Success
Transition pedagogy is a whole-of-institution approach for supporting learning across diverse student cohorts through intentional, integrated (co-)curricular design.
Ryan Naylor
doaj   +1 more source

Session 47: Menstruation matters: exploring how menstruation influences the student experience at LJMU

open access: yes
Session overview: This session will present the findings and recommendations from an ongoing piece of research called Menstruation Matters.  This project has been funded by the LMU EDI fund and is set to explore the experience of students who menstruate,
Neary, Katherine, Dale, Gemma
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

On the Use of Large Language Models for Improving Student and Staff Experience in Higher Education

open access: yesOpen Education Studies
Large language models (LLMs) hold great promise for enhancing teaching and learning in higher education, yet educators and administrators still lack practical examples to guide their adoption.
O’Neill Sam   +2 more
doaj   +1 more source

Seen and Supported: Implementing a University-Wide Transition Framework to Improve First-Year Success

open access: yesStudent Success
A Transition Pedagogy framework acknowledges students’ transition into university from diverse backgrounds, with varied preparedness for studying at university.
Kelly Linden   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy