An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
The multi-parameter optimized belief rule base for predicting student performance with interpretability. [PDF]
Li J +6 more
europepmc +1 more source
Does performance related pay for teachers improve student performance? Some evidence from India [PDF]
In this paper data from a school survey in India is used to ask if there is evidence for the payment of performance related pay and whether such pay structures do impact on student achievement.
Francis Teal, Geeta G. Kingdon
core
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
How well do admission criteria predict student performance in one medical course? [PDF]
Althewini A.
europepmc +1 more source
UNDERGRADUATE STUDENT PERFORMANCE
The Doan Truong, Xiem Thuy Cao
openaire +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
Explainable AI in education: integrating educational domain knowledge into the deep learning model for improved student performance prediction. [PDF]
Qiang M, Liu Z, Zhang R.
europepmc +1 more source
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Correction: MultiFAR: Multidimensional information fusion with attention-driven representation learning for student performance prediction. [PDF]
Fazil M, Albahlal BM.
europepmc +1 more source

