Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux +7 more
wiley +1 more source
Munirah Batarfi,1 Abdulrahman Alraddadi2– 4 1Department of Anatomy, College of Medicine, King Saud University, Riyadh, Saudi Arabia; 2Department of Basic Medical Sciences, College of Medicine, King Saud bin Abdulaziz University for Health Sciences ...
Batarfi M, Alraddadi A
doaj
The effect of haptic virtual reality simulation training before clinical endodontic practice on student performance and perception. [PDF]
Şimşek E, Satar S.
europepmc +1 more source
Academic performance of dental students
P D, Barnard, S K, Siu
openaire +3 more sources
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Artificial test-takers as transformed controls: measuring SAT difficulty drift and student performance. [PDF]
Suresh VK, Rawat S.
europepmc +1 more source
Smaller is better: nanobodies meet NMR
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
Determinants of Student Retention of Microeconomic Concepts [PDF]
In this study, we examine a variety of individual, institutional, and course-specific factors that influence students' retention of concepts from the microeconomics principles course.
Larry Spizman, John Kane
core
Retraction: TGEL-transformer: Fusing educational theories with deep learning for interpretable student performance prediction. [PDF]
PLOS One Editors.
europepmc +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source

