Results 131 to 140 of about 534,772 (185)

Knowing Me Knowing You-Mentorship in Hospital Placement. [PDF]

Clin Teach
Kvernenes M, Grimstad H, Schei E, Thyness C, Dornan T, Stenfors T.   +5 more
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Abstracts of the 18th Academic Medical Congress of Piaui

International Journal of Medical Students, 2013
International Journal of Medical Students
doaj  

Closing the Numeracy Gap in Medication Safety: Impact of a safeMedicate Intervention in Undergraduate Medical Education. [PDF]

Pharmacol Res Perspect
Sadiq S, Driver S, Gschwandtner M.
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

Abstracts of the 4th Annual International Medical Students Meeting

International Journal of Medical Students, 2013
International Journal of Medical Students
doaj  

Comparison of Physician Assistant and Medical Students' Clinical Reasoning Processes Using an Online Patient Simulation Tool to Support Clinical Reasoning (eCREST): Mixed Methods Study.

JMIR Med Educ
Thorpe A, Kassianos AP, Plackett R, Krishnamurthy V, Kambouri MA, Sheringham J.   +5 more
europepmc   +1 more source

Ultrasound as a Foundational Tool in Medical Education: A Literature Review. [PDF]

Adv Med Educ Pract
Provenzano SM, Mageto I, González Frontera A, Uter C, Casey S, Badillo A, Fakoya AOJ.   +6 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Turning Chairs, Opening Minds: Redesigning Feedback in Medical Clerkships. [PDF]

Clin Teach
Spinnewijn L, de Jong EN, van Altena AM, van Dillen J, Fluit LCRMG, de Groot A.   +5 more
europepmc   +1 more source