Results 131 to 140 of about 10,956,794 (321)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Download the complete supplement in one PDF

open access: yesInternational Journal of Medical Students, 2013
International Journal of Medical Students
doaj   +6 more sources

Interprofessional Education (IPE) Activity amongst Health Sciences Students at Sultan Qaboos University : The time is now!

open access: yesSultan Qaboos University Medical Journal, 2012
Historically, health professionals have been educated in profession-specific institutions which provide limited opportunities for learning interprofessional (IP) skills.
Ibrahim M. Inuwa
doaj  

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

open access: yesFEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue   +6 more
wiley   +1 more source

Percepción de estudiantes y profesores acerca del contenido económico en la formación de los estudiantes de la carrera de Medicina

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2019
Fundamento: el médico general ejerce su profesión en los campos de atención médica integral, administrativo, educativo e investigativo; debe formarse para ello.Objetivo: describir la percepción de profesores y estudiantes, de la Facultad de Ciencias ...
Nilvia Norma Agüero-Batista   +2 more
doaj  

Sexual and Reproductive Health in Rwanda [PDF]

open access: yes, 2016
KEY MESSAGES Empowerment (women, youth, communities) Inclusion (age + gender) Prevention/Early Detection PROGRAM RECOMMENDATIONS Partner with Rwandan medical students to improve program delivery Communicate monthly with local leaders Partner with ...
Zhang, Emily
core   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

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