Results 131 to 140 of about 11,514,366 (252)

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Career choices among medical students in Bangladesh

, 2011
SM Moslehuddin Ahmed1, Md Anwarul Azim Majumdar2, Rezina Karim3, Sayeeda Rahman2, Nuzhat Rahman41Department of Community Medicine, Uttara Adhunik Medical College, Dhaka, Bangladesh; 2Department of Clinical Sciences, School of Life Sciences, University of
SM Moslehuddin Ahmed, et al, Md Anwarul Azim Majumdar, Rezina Karim   +3 more
core  

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

The impact of personal, family, and educational environment factors on awareness of professionalism among health science students

Revista Cubana de Medicina Militar
Background: Awareness of professionalism is essential for students in health sciences, as it supports effective learning, ethical conduct, and professional development, and plays a crucial role in shaping their future careers. Objective: To assess the
Minh Huu Le, Tan Dat Nguyen, Ngoc Huyen Nguyen, Thi Kieu Lan Nguyen, Van Leo Le, Trung Chi Minh Nguyen, Van Trang Do, Thi Hong Tuyen Nguyen   +7 more
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

PowerPoint or chalk and talk: Perceptions of medical students versus dental students in a medical college in India

, 2010
Vikas Seth, Prerna Upadhyaya, Mushtaq Ahmad, Vijay MogheDepartment of Pharmacology, Mahatma Gandhi Medical College, Jaipur, Rajasthan, IndiaPurpose: To assess students’ perceptions of the impact of PowerPoint (PPT) presentations in lectures in ...
Mushtaq Ahmad, Prerna Upadhyaya, Vikas Seth, et al.   +3 more
core  

Research on medical students' medical ethics reasoning ability-analysis based on the intermediate concept measurement method. [PDF]

BMC Med Ethics
Feng C, Zhang X, Zhang L.
europepmc   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Training Medical Students/Medical Practitioners to Diagnose Dermatologic Conditions in Skin of Color: A Systematic Review of Educational Interventions. [PDF]

J Cutan Med Surg
Lee AD, Thandi A, Choi J, Xiong G, Pollanen S, Rachel Yee KA, Jafarian F, Sibbald C.   +7 more
europepmc   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source