Results 111 to 120 of about 309,992 (313)
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Frontiers in Public HealthIn recent years, nuts have gained importance because of their nutritional benefits in promoting health and preventing chronic diseases. Despite their recognized role as part of healthy dietary patterns, global consumption is below recommended levels ...
Ivana Stević +6 more
doaj +1 more source
Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes
FEBS Open Bio, EarlyView.We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde +3 more
wiley +1 more source
Scaffolding patient counselling skills in Australian university pharmacy programs. [PDF]
, 2010 This paper presents the results of an appraisal of the extent of, and approaches to, scaffolding for development of counseling skills of pharmacy students across Australian universities. There were two stages in the work.
McKauge, Leigh +4 more
core
Aging and Cancer, EarlyView.Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath +3 more
wiley +1 more source
Drug, Healthcare and Patient SafetyBukoli Brian,1 Narayana Goruntla,1 Bhavana Reddy Bommireddy,2 Bhavani M Mopuri,2 Vigneshwaran Easwaran,3 Mohammad Jaffar Sadiq Mantargi,4 Durga Prasad Thammisetty,5 Sarad Pawar Naik Bukke,6 Tadele Mekuriya Yadesa,1 Ebere Emilia Ayogu7 1Department of ...
Brian B +9 more
doaj
Developing a Pharmacy Professional Elective Course: Underserved Populations [PDF]
, 2007 Objectives. To ascertain the current curriculum exposure, knowledge, and interest in medically underserved populations of 3rd and 4th year professional pharmacy students enrolled at Butler University. Methods.
Hedrick, Courtney Ann
core +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Barriers to medication counselling for people with mental health disorders: a six country study
Pharmacy Practice, 2010 Provision of medication information may improve adherence and prevent medication related problems. People with mental health disorders commonly receive less medication counselling from pharmacists than people with other common long term and persistent ...
Aaltonen SE +10 more
doaj