Results 101 to 110 of about 233,603 (267)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The relationship between mindfulness, self-control, and short video addiction among medical students

Frontiers in Psychology
BackgroundThe prevalence of short video addiction is rising among college students, potentially exerting detrimental effects on their physical and mental wellbeing.
Yuting Luo, Yulian Li, Quanmin Wu, Pengchong Shi   +3 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Effects of loneliness on short video addiction among college students: the chain mediating role of social support and physical activity

Frontiers in Public Health
Loneliness is a common public health problem that affects physical and mental health. Prior research has demonstrated a connection between internet addiction and loneliness. Short video addiction is a novel internet addiction.
Zhe Zhao, Yali Kou
doaj   +1 more source

Problematic overstudying: Studyholism or study addiction? [PDF]

J Behav Addict, 2018
Loscalzo Y, Giannini M.
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

The Longitudinal Relationship Between Sibling Smartphone Addiction and Child Smartphone Addiction

Psychology Research and Behavior Management
Myeong Sook Yoon,1 Kyu Hyoung Jeong,1 Heeran J Cho2 1Department of Social Welfare, Jeonbuk National University, Jeonju, South Korea; 2Department of Biohealth, Kyungwoon University, Gumi, South KoreaCorrespondence: Kyu Hyoung Jeong, Jeonbuk National ...
Yoon MS, Jeong KH, Cho HJ
doaj  

The relationship between work addiction and addictions to social media, shopping, food, caffeine, and nicotine

Australian Journal of Psychology
Purpose Work addiction is a relatively underexplored behaviour compared to other forms of addiction. Existing research predominantly focuses on the antecedents and consequences of work addiction.
Emrah Özsoy, Mark D. Griffiths, Gülay Tınmaz Karaçay, Ömer Alperen Onay, Canan Yılmaz, Özlem Balaban   +5 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source