Results 101 to 110 of about 622,021 (312)

In Search of Factors to Online Game Addiction and its Implications [PDF]

, 2007
Research has explored online users who are hooked on Internet applications such as chat rooms, web surfing, and interactive games. Online game addiction is one of the problems arisen from the use of the Internet.
Chen, Jeng-Chung V, Park, Yangil
core   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

GABA-B receptor function in healthy volunteers, a pharmacokinetic and pharmacodynamic study of two doses of baclofen compared to placebo [PDF]

, 2015
AIMS AND HYPOTHESIS To assess the subjective and objective effects of baclofen on brain function in healthy volunteers. BACKGROUND Recent evidence suggests baclofen, a γ-aminobutyric acid type B (GABA-B) receptor agonist, reduces alcohol consumption ...
Cordero, R, Durant, C, Lingford-Hughes, A, Nahar, L, Nutt, D, Paterson, S, Turton, S, Wilson, S   +7 more
core  

Prevalence of internet addiction disorder in Chinese university students: A comprehensive meta-analysis of observational studies [PDF]

, 2018
Background and aims: Internet addiction disorder (IAD) is common in university students. A number of studies have examined the prevalence of IAD in Chinese university students, but the results have been inconsistent.
Chai, Jing-Xin, Li, Lin, Li, Lu, Lu, Li, Mei, Song-Li, Ng, Chee H, Ungvari, Gabor S, Wang, Di, Xiang, Yu-Tao, Xu, Dan-Dan, Zhang, Ling   +10 more
core   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Factors associated with drug addiction relapse in elderly adults in Iran: A cross-sectional study [PDF]

Journal of Nursing Reports in Clinical Practice
Drug addiction relapse always complicates the process of coping with the addiction. Being aware of drug addicts’ attitudes toward barriers to permanent withdrawal can significantly affect the prevention of addiction relapse.
Zahra Abedi, Yasaman Yaghobi, Parand Pourghane, Elnaz Faraji Nesfechi   +3 more
doaj   +1 more source

Maternal Drug Addiction: Influences on mother-child relationship and on early child development. [PDF]

, 2016
Much literature has pointed out parental drug addiction as a risk factor at multiple levels for the dyad, affecting parenting quality, child development and more globally the adult-child relationship.
DE PALO, Francesca, Porreca, Alessio, Simonelli, Alessandra   +2 more
core  

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Developing practical strategies to reduce addiction-related stigma and discrimination in public addiction treatment centers: a mixed-methods study protocol

Addiction Science & Clinical Practice
Background People with substance use disorders (SUDs) have restricted engagement with health-care facilities and describe repeated experiences of stigma, discrimination, and mistreatment when receiving care at health-care and public addiction treatment ...
Maryam Khazaee-Pool, Seyed Abolhassan Naghibi, Tahereh Pashaei, Koen Ponnet   +3 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source