Results 141 to 150 of about 14,586,279 (354)

A critical evaluation of methodological and mechanistic insights on probiotic-derived extracellular vesicles

open access: yesFrontiers in Nutrition
Probiotic extracellular vesicles (pEVs) have emerged as promising postbiotics with potential applications in inflammatory diseases, infections, allergies, cancer treatment, autoimmune disorders, and even neurological and degenerative conditions.
Chantal Ronacher   +2 more
doaj   +1 more source

A study to assess the effects of a broad-spectrum immune modulatory therapy on mortality and morbidity in patients with chronic heart failure: The ACCLAIM trial rationale and design [PDF]

open access: bronze, 2007
Guillermo Torre‐Amione   +10 more
openalex   +1 more source

Accelerator systems for the international design study of the neutrino factory [PDF]

open access: yes, 2011
The Neutrino Factory produces high-energy neutrino beams with a well-defined flavour content and energy spectrum from the decay of intense, high-energy, stored muon beams.
Soler, F.J.P.
core  

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

open access: yesFEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira   +3 more
wiley   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer

open access: green, 2020
Md Ashraf-Uz-Zaman   +12 more
openalex   +2 more sources

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