Results 151 to 160 of about 14,586,279 (354)
Correction: Using a design-based research methodology to develop and study prompts integrated into GeoGebra to support mathematics learning of gifted students [PDF]
, 2023 Esmaeil Azimi +2 more
openalex +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Using Combinatorial Design to Study Regulation by Multiple Input Signals. A Tool for Parsimony in the Post-Genomics Era [PDF]
, 2001 D. E. Shasha
openalex +1 more source
Advanced heat receiver conceptual design study [PDF]
Solar Dynamic space power systems are candidate electrical power generating systems for future NASA missions. One of the key components of the solar dynamic power system is the solar receiver/thermal energy storage (TES) subsystem.
Batchelder, Gary +2 more
core +1 more source
FEBS Letters, EarlyView.This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Preliminary design study of a baseline MIUS [PDF]
Results of a conceptual design study to establish a baseline design for a modular integrated utility system (MIUS) are presented. The system concept developed a basis for evaluating possible projects to demonstrate an MIUS.
Gill, W. L. +8 more
core +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
E-Journal of Cultural Studies, 2013 Postreality representation of design of the Building of the Government Center of Badung Regency is interesting to explore as it is designed using the most recent simulation.
I Gede Mugi Raharja
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