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Study Design for Sequencing Studies
2016Once a biochemical method has been devised to sample RNA or DNA of interest, sequencing can be used to identify the sampled molecules with high fidelity and low bias. High-throughput sequencing has therefore become the primary data acquisition method for many genomics studies and is being used more and more to address molecular biology questions.
Martin Krzywinski +2 more
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Journal of American College Health, 1996
Abstract Building upon an initial article, which described the processes of literature review and hypothesis development, the authors summarize issues of research design. General issues encountered by researchers in college health settings include the establishment of a clear research focus, selection of a representative and adequate study sample, use ...
Ralph A Manchester, Brett N. Steenbarger
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Abstract Building upon an initial article, which described the processes of literature review and hypothesis development, the authors summarize issues of research design. General issues encountered by researchers in college health settings include the establishment of a clear research focus, selection of a representative and adequate study sample, use ...
Ralph A Manchester, Brett N. Steenbarger
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2018
This chapter deals with the design of the study, which includes different phases of research work. The details of the work done in each phase along with the tools, techniques, and models used have been explained.
Jagdeep Singh, Harwinder Singh
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This chapter deals with the design of the study, which includes different phases of research work. The details of the work done in each phase along with the tools, techniques, and models used have been explained.
Jagdeep Singh, Harwinder Singh
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The chapter starts by setting out the research questions guiding the study. It explains the comprehensive, systematic, critical, accessible and decolonial approach used to review the global literature. It then sets out the co-creative approach that was used in working with teachers to develop the book.
Leon Tikly +13 more
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Leon Tikly +13 more
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2019
This chapter presents the analytical scheme and research questions guiding the study of the Bibliometric Research Indicator (BRI). The design, methods and data sources are presented, and different methodological issues are discussed. The analyses are based on quantitative and qualitative data in the form of questionnaires (surveys) and interviews with ...
Poul Erik Mouritzen, Niels Opstrup
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This chapter presents the analytical scheme and research questions guiding the study of the Bibliometric Research Indicator (BRI). The design, methods and data sources are presented, and different methodological issues are discussed. The analyses are based on quantitative and qualitative data in the form of questionnaires (surveys) and interviews with ...
Poul Erik Mouritzen, Niels Opstrup
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Journal of Lower Genital Tract Disease, 2015
To aid authors in correctly naming their study design, to assist readers and reviewers who must decide what the design was for some published studies, and to provide consistency in evaluating the design of published studies, especially for those conducting systematic reviews and evidence synthesis.An annotated algorithm method is used to prompt serial ...
Jeffrey C Andrews, Frances E Likis
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To aid authors in correctly naming their study design, to assist readers and reviewers who must decide what the design was for some published studies, and to provide consistency in evaluating the design of published studies, especially for those conducting systematic reviews and evidence synthesis.An annotated algorithm method is used to prompt serial ...
Jeffrey C Andrews, Frances E Likis
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, 2014 This chapter, Design of the Study, gives the motivation of the choice of the study and the description of the scientific and the societal impact of the study. The main concepts used in the study are introduced and explained. The research problem is formulated and operationalized as a set of research questions. Some of the theoretical and methodological
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Designing Physiogenomic Studies
Pharmacogenomics, 2006‘The increase in sample size needed to account for multiple testing is relatively modest, increasing only logarithmically with the number of markers, thus remaining quite feasible even for genome-wide SNP arrays.’ Micro- and nano-array technologies can produce millions of biomarkers for biomedical research.
Andreas Windemuth +2 more
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2020
This chapter is mainly about the nature and design of the study. It starts with the justification for using a qualitative multi-case study approach in this study. It then introduces the selection of the research setting, target curriculum materials and teacher and student participants.
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This chapter is mainly about the nature and design of the study. It starts with the justification for using a qualitative multi-case study approach in this study. It then introduces the selection of the research setting, target curriculum materials and teacher and student participants.
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Design of toxicokinetic studies
Xenobiotica, 19901. Toxicokinetics is defined as pharmacokinetic studies in animals during actual toxicity studies or under conditions mimicking them (species, duration, dose level, etc.). 2. Toxicology studies require toxicokinetics to check whether systemic exposure reflects administered dose.
Dennis A. Smith +2 more
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