Results 231 to 240 of about 14,586,279 (354)

Adapting Restorative Urban Design, for Open Spaces Towards, Thermal Heat Island, Reaching Human Mental Health and Well-being, Case study: Qaitbay Citadel Plaza, Alexandria, Egypt

M. Nasr, Sarwan Ali, Abdelaziz Farouk Mohamed   +2 more
openalex   +2 more sources

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

Molecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui, Matthew A. Cottam, Muhammad Bilal Mirza, Keeli B. Lewis, Kristen K. Ciombor, Mary Kay Washington, Kamran Idrees   +6 more
wiley   +1 more source

Creation of a Support Tool for the Needs Assessment Process: A Design and Development Study

, 2020
Carmalita Trotman
openalex   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

Molecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad, Mahmood Hachim, Tom Bertin, Karolina Penderecka, Rifat Hamoudi, Saif Khan, Rui Henrique, Natalie Bergmoser, Manit Arya, Kalle Sipila, Matteo Vietri Rudan, Asif Muneer, Aamir Ahmed   +12 more
wiley   +1 more source

Comment on Long-Term Pulmonary Sequelae Following Severe COVID-19: Reflections on Study Design and Interpretation. [PDF]

Ann Am Thorac Soc
Li W, Jiang J.
europepmc   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

Molecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck, Nele De Meulenaere, Thomas Vanpoucke, Joe Ibrahim, Dieter Peeters, Suresh Krishan Yogeswaran, Wen Wen, Paul Van Schil, Jeroen M. H. Hendriks, Jo Raskin, Jan van Meerbeeck, Guy Van Camp, Ken Op de Beeck   +12 more
wiley   +1 more source

Considerations for study design and analysis for ethically and culturally safe DNA methylation research in Aotearoa New Zealand. [PDF]

SSM Popul Health
Rolleston A, Jones GT, Earle NJ, Gibbs S, Pilbrow A, Faatoese A, Poppe KK, Henare K, Cameron VA, Macartney-Coxson D, Legget ME, Doughty RN.   +11 more
europepmc   +1 more source

Deep Exploration of Teaching Reform in "Petroleum and Natural Gas Geology Curriculum Design" Oriented by National Oil and Gas Geology Competition-A Case Study of Shandong University of Petroleum and Chemical Technology [PDF]

Yuzuo Liu, Jiao Wang, Jie Chen
openalex   +1 more source