Results 251 to 260 of about 14,586,279 (354)

Ideal Library Design From Children's Perspective: A Phenomenological Study [PDF]

Erol Yılmaz, Ali Kavak
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Heterogeneous Network With Multiview Path Aggregation: Drug-Target Interaction Prediction Study Design.

JMIR Med Inform
Zhao H, Yao K, Liu Y, Che C, Tang L.
europepmc   +1 more source

Universal Study Design for Instrument Changes in Pharmaceutical Release Analytics. [PDF]

Electrophoresis
Ries AB, Merkel MN, Coßmann K, Paul M, Grunwald R, Klemmer D, Hübner F, Eggensperger S, Weiß FT.   +8 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

The Wako Cohort Study: Design and Profile of Participants at Baseline. [PDF]

J Epidemiol
Yokoyama Y, Nofuji Y, Abe T, Nonaka K, Ozone Y, Nakamura Y, Chiaki S, Suda T, Saito N, Takase M, Amano H, Ogawa S, Suzuki H, Murayama H.   +13 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Assessing residential neighborhood exposomes and their associations with cancer incidence: rationale, study design, and methods. [PDF]

Am J Epidemiol
Jones RM, Han I, Hughes J, Nelson EJ.
europepmc   +1 more source