Results 111 to 120 of about 35,019,213 (291)

A study of engagement in casual leisure occupations by individuals who are living with neuropalliative conditions

, 2013
Purpose. This study explored the following research questions:1. What are the normal and sensory-overloaded behaviours exhibited by adults living with neuropalliative conditions?2.
Fenech, Anne
core   +1 more source

Soft motions encoded by the fold and mediated by conserved hinge sites drive V‐ATPase allosteric machinery and autoinhibition

FEBS Letters, EarlyView.
Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana, Xiaowei Bogetti, Stuti Sharma, Ivet Bahar   +3 more
wiley   +1 more source

Office for Public Engagement: Community Partnership Development and Leadership

, 2008
University of Minnesota: Office for Public Engagement. (2008). Office for Public Engagement: Community Partnership Development and Leadership.
University of Minnesota: Office for Public Engagement
core  

Studyholism and Attachment Style: A Study among Italian University Students

Behavioral Sciences
Studyholism (or obsession with studying) is a new potential clinical condition introduced in the literature in 2017. Since then, growing research has supported its conceptualization as a clinical disorder and highlighted some potential intervention ...
Yura Loscalzo, Marco Giannini
doaj   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Administrative Advisory Committee for Public Engagement/Outreach Final Report

, 2002
University of Minnesota: Office for Public Engagement. (2002). Administrative Advisory Committee for Public Engagement/Outreach Final Report.
University of Minnesota: Office for Public Engagement
core  

The puzzle of engagement: An interview study on the subjective experience of engagement with mainstream narrational complexity.

Psychology of Popular Media
Structurally complex narratives, characterized by nonlinear chronology, shifting perspectives, or multi-layered story worlds, have become increasingly prominent in mainstream film and television. While scholars have theorized the aesthetic and cognitive implications of these narratives, we know far less about how viewers actually experience them.
Gaia Yonah, Cynthia Cabanas, Steven Willemsen, Miklós Kiss, Frank Hakemulder, Mariken Anna Catharina Geertruida van der Velden, Elly Konijn, Katalin Bálint   +7 more
openaire   +2 more sources

How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome

FEBS Letters, EarlyView.
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini, Freia S. Buus, Benjamin Schuler, Birthe B. Kragelund   +3 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Office for Public Engagement: Accounting and Assessment Task Force

, 2008
University of Minnesota: Office for Public Engagement. (2008). Office for Public Engagement: Accounting and Assessment Task Force.
University of Minnesota: Office for Public Engagement
core