Results 131 to 140 of about 35,019,213 (291)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Engagement and interaction in blended workplace learning: A case study [PDF]

open access: yes, 2016
This thesis is based on a case study of blended workplace learning, investigating learner engagement and interaction in a blended learning program. Results show that various individual, workplace, and program factors influence learner engagement and ...
Hewett, Suniti
core  

Examining bedtime procrastination, study engagement, and studyholism in undergraduate students, and their association with insomnia. [PDF]

open access: yesFront Psychol, 2022
Alshammari TK   +7 more
europepmc   +1 more source

A Study of Employee Engagement

open access: yes, 2009
The Institute of Development Studies (IDS) 2007 described Employee Engagement as "a step up from employee satisfaction, denoting a level of commitment to the organisation characteristic of high performing staff. An engaged employee is one who is passionate about their job, loyal to the organisation and dedicated to their work. They are likely to have a
openaire   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Perspectives on Institutional Accountability and Public Engagement

open access: yes, 2003
University of Minnesota: Council on Public Engagement, Ziegenhagen, John. (2003). Perspectives on Institutional Accountability and Public Engagement.
University of Minnesota: Council on Public Engagement, Ziegenhagen, John
core  

Organisational climate and its effect on job engagement: exploring the mediating effect of employees level of job satisfaction [PDF]

open access: yes, 2013
This study examined two under-researched organisational climate facets, integration and family-focused supervisor support, as predictors of employees' job engagement.
Koch, Timothy C
core   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim   +17 more
wiley   +1 more source

National Survey of Student Engagement 2023 Engagement Indicators (Lake Campus)

open access: yes, 2023
This National Survey of Student Engagement reports summary measures based on sets of NSSE questions examining key dimensions of student ...
National Survey of Student Engagement
core  

“Making Gymnastics Enjoyable and Sustainable:” Positioning Gymnastics in Physical Education through Individual Interest Bolstering Study Engagement for a Lifelong and Healthy Lifestyle

open access: yesPhysical Culture and Sport: Studies and Research
While individual interest has been widely associated with student engagement across academic domains, its role in specialized physical education courses like gymnastics remains underexplored in Philippine higher education.
Lobo Joseph
doaj   +1 more source

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