Frontiers in Public HealthBackgroundDelayed or reduced antenatal care use by pregnant women may result in poorer outcomes. ‘Candidacy’ is a synthetic framework which outlines how people’s eligibility for healthcare is jointly negotiated.
Tisha Dasgupta +7 more
doaj +1 more source
Evaluation of Study Engagement With an mHealth Intervention (THR1VE) to Treat Diabetes Distress in Teens With Type 1 Diabetes: Randomized Clinical Trial. [PDF]
JMIR Pediatr Parent, 2023 LeStourgeon L +4 more
europepmc +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Engaging Social Stakeholders in National Asbestos Research for Public Health: An Italian Experience
Annals of Global HealthBackground: Asbestos and its impacts on the population worldwide are threats to the environment and public health, striking both countries that have banned asbestos, such as Italy in 1992, and those that continue its use.
Daniela Marsili +5 more
doaj +1 more source
Heavy Study Investment: An Analysis of the Defense Mechanisms Characterizing Studyholism and Study Engagement. [PDF]
Int J Environ Res Public Health, 2022 Loscalzo Y, Giannini M.
europepmc +1 more source
Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Performance Assessment through Work Gamification: Investigating Engagement
South African Journal of Business ManagementPurpose: The purpose of this study is to evaluate, investigate and assess the impact of gamification on the performance of online transportation drivers via social values, motivation and participatory engagement.
Honorata R.D. Putranti +3 more
doaj +1 more source
Studyholism and Study Engagement in Adolescence: The Role of Social Anxiety and Interpretation Bias as Antecedents. [PDF]
Int J Environ Res Public Health, 2022 Loscalzo Y, Giannini M.
europepmc +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Community Engagement newsletter, Faculty of Veterinary Science, Winter, 2011 [PDF]
, 2011 Originally published as HTML file, converted to PDF with Adobe Acrobat 9 Pro Version 9.0.0.News articles with colour photos about the various community engagement projects of the Faculty of Veterinary Science, University of Pretoria.Introduction to ...
Pretorius, Minette +13 more
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