Results 71 to 80 of about 42,227 (309)

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Studying minority languages in the linguistic landscape [PDF]

Being visible may be as important for minority languages as being heard. Traditional research on minority languages focuses on language maintenance and language shift, on language endangerment and revitalization, on language transmission in the family ...
Marten, Heiko F., Van Mensel, Luk, Gorter, Durk   +2 more
core   +1 more source

Do bilinguals have different concepts? The case of shape and material in Japanese L2 users of English [PDF]

, 2006
An experiment investigated whether Japanese speakers’ categorisation of objects and substances as shape or material is influenced by acquiring English, based on Imai and Gentner (1997).
Sasaki, Miho, Takahashi, J., Kasai, C., Bassetti, Benedetta, Takahashi, Jun Arata, Bassetti, Benedetta; id_orcid, Cook, V., Jun Arata Takahashi, Chise Kasai, Kasai, Chise, Miho Sasaki, Sasaki, M., Cook, Vivian, Vivian Cook, Benedetta Bassetti   +14 more
core   +1 more source

ONLINE-TANDEM IN POST-INTERCULTURAL COMMUNITY: SELF-EDUCATION IN COOPERATION

Polylinguality and Transcultural Practices, 2017
The concept “cultures” lost a clear boundary today: only in the sphere of studying and teaching foreign languages it is possible to speak about the standard of speech - verbal and nonverbal aspect; to culture of behavior, culture of clothes, etc.; and ...
Ekaterina Lvovna Kudryavtseva, Larisa Borisovna Bubekova   +1 more
doaj   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

International languages in primary schools: Aims, constraints, and one way forward

, 2006
The present policy of the Ministry of Education is that all schools should offer instruction in an additional language from Year 7 to Year 10. The additional languages may be te reo Māori, a Pacific language, or one of several international languages ...
Barnard, Roger
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PROBLEMS TO LEARN LANGUAGES

, 2023
<p><i>This article discusses the problems that learners confront while learning new languages. Experienced teachers know what difficulties most often arise for students studying foreign languages.
Jabborova, Aziza
core   +1 more source

TEACHING A FOREIGN LANGUAGE USING INTERACTIVE TEACHING METHODS IN INSTITUTIONS EDUCATION OF THE I-II LEVEL OF ACCREDITATION

Освітній вимір, 2008
In article to be considered effectiveness of using interactive methods of studying in the process of learnin foreign languages in higher educational of 1-11 degrees of accreditation.
N.O. Stepanchuk, M.O. Ahaponenko
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

Seven hundred reasons for studying languages

, 2004
New research by the UK Subject Centre for Languages has identified more than 700 reasons to study languages. It concludes that the strongest of these reasons are the personal benefits and enjoyment that people gain from learning a language.
Gallagher-Brett, Angela
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