Results 81 to 90 of about 42,227 (309)

COMPUTER TECHNOLOGIES FOR KNOWLEDGE VISUALIZATION IN NATIVE LANGUAGES STUDYING [PDF]

, 2015
В статье ставится задача рассмотреть виды компью- терных технологий для визуализации знаний в изучении родного языка. Выявлена и обоснована необходимость изучать родной язык, используя информационно-коммуникативные технологии.
Хисматуллина Регина Борисовна, Пиранишвили Мамука Артилович   +1 more
core  

COMMUNICATION: FUNCTIONS OF COMMUNICATION FROM THE PERSPECTIVE OF STUDYING FOREIGN LANGUAGES

Studia Universitatis Moldaviae: Stiinte ale Educatiei, 2019
COMUNICAREA: FUNCȚIILE COMUNICĂRII DIN PERSPECTIVA STUDIERII LIMBILOR STRĂINE În articol este abordată problema comunicării ca fenomen social, accentul fiind pus pe analiza funcțiilor comunicării, pe competențele de comunicare în limbile străine din ...
USM ADMIN
doaj  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Semantic subtyping for imperative object-oriented languages

, 2016
Semantic subtyping is an approach for defining sound and complete procedures to decide subtyping for expressive types, including union and intersection types; although it has been exploited especially in functional languages for XML based programming ...
CORRADI, ANDREA, Davide Ancona, Andrea Corradi, ANCONA, DAVIDE   +3 more
core   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Iranian languages and scripts [PDF]

, 2009
This article aims to investigate the Iranian languages and their changes down through history, especially the Persian language or Farsi. In addition to the languages, Persian scripts and their development have been studied.
Matindoost, Ahmad
core  

СЛАВЯН ТІЛДЕРІНДЕГІ ТҮРКИЗМДЕРДІҢ ЗЕРТТЕЛУ ТАРИХЫ

Әл-Фараби Атындағы Қазақ Ұлттық Университеті хабаршы шығыстану сериясы, 2016
В этой статье рассматривается вопросы изучения тюркизмов в славянских языках, пути проникновения, проблемы взаимовлияния и взаимообогащения контак- тирования языков.
Ұ. Т. Алжанбаева
doaj  

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

A Computational Model for Studying the Characteristics of Languages using Coded Character Sets

, 2020
Computer languages possess the structure for studying all categories of languages due to the fact that all languages have basic character sets which are the fundamental building blocks for their syntaxes.
manager, journal
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source