Results 91 to 100 of about 3,557,572 (375)
Evolutionary interplay between viruses and R‐loops
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi+4 more
wiley +1 more source
Benchmarking of a software stack for autonomous racing against a professional human race driver
The way to full autonomy of public road vehicles requires the step-by-step replacement of the human driver, with the ultimate goal of replacing the driver completely.
Betz, Johannes+2 more
core +1 more source
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
[BOOK REVIEW] DEVELOPING INTERACTIONAL COMPETENCE IN A JAPANESE STUDY ABROAD CONTEXT
(Developing Interactional competence in A Japanese Study Abroad Context) is a book focusing on second language learning acquisition by Naoko Taguchi. It is a study describing the process of second language acquisition which focuses on the development of ...
Lisda Nurjaleka
doaj +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi+3 more
wiley +1 more source
Scare-quoting and incorporation [PDF]
I explain a mechanism I call “incorporation,” that I think is at work in a wide range of cases often put under the heading of “scare-quoting.” Incorporation is flagging some words in one’s own utterance to indicate that they are to be interpreted as if ...
McCullagh, Mark
core
Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi+26 more
wiley +1 more source
This paper addresses the style-shifting of podcast host Sarah Koenig, specifically in her use of utterance final creaky voice in different contexts.
Edgar Yau
doaj +1 more source
The economic effects of alternative fee shifting rules: A review of the theoretical and empirical literature [PDF]
The so-called English Rule in § 91 ZPO has a longstanding tradition in German civil litigation. Although this “loser pays”- fee shifting can raise severe problems like sharply reducing access to the courts for parties of moderate means, the adaption of ...
Schwab, Christian, Tang, Hin-Yue Benny
core +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source