Results 91 to 100 of about 30,604 (290)

Variation and sociolinguistic competence in children’s talk at school

open access: yesRicerche di Pedagogia e Didattica
This study analyses how children switch between varieties of Italian during classroom interaction, based on video recordings from third-grade classes in four Lazio schools (Colleferro, Pomezia, Valmontone, Frosinone).
Elisa De Roberto, Sabrina Rizzello
doaj   +1 more source

Volume 5, Issue 1

open access: yesInternational Journal of the First Year in Higher Education, 2014
The Feature in this issue is a conversation with Richard James, a highly respected Australian academic with extensive experience in research and policy development on the First Year Experience.
Karen Nelson, John Clarke, Tracy Creagh
doaj   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

Locating Style: Style-shifting to Characterize Community at the Border of Washington, D.C. [PDF]

open access: yes, 2013
While a number of sociolinguistic studies have examined intraspeaker variation and how it allows a speaker to negotiate identities related to class, much of the existing work on speakers and their physically-delimited communities has focused on ...
Grieser, Jessica
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Language Style as Identity Construction: A Footing and Framing Approach [PDF]

open access: yes, 1998
Despite the prevalence of conceptualizations of style shifting as a reactive phenomenon, conditioned by contextual factors such as formality and audience, style shifting increasingly has come to be viewed as a proactive phenomenon which speakers freely ...
Kiesling, Scott F   +3 more
core  

Rethinking the Ornament with/in Luigi Nono’s Late Electroacoustic Works

open access: yesMusica Theorica, 2019
This paper aims at examining the manifestations of the ornamental phenomenon in the musical project that Luigi Nono developed in the last ten years of his life.
Kevin Gohon
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

He Said, She Said: Style Transfer for Shifting the Perspective of Dialogues [PDF]

open access: yes, 2022
In this work, we define a new style transfer task: perspective shift, which reframes a dialogue from informal first person to a formal third person rephrasing of the text.
Bertsch, Amanda   +2 more
core   +1 more source

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