Results 111 to 120 of about 549,704 (368)

Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi   +3 more
wiley   +1 more source

Models of digitisation of organisational space in sport

open access: yesJournal of Education, Health and Sport, 2019
This research presents the organisational model of digitisation of sport institutions as the element of development shifting towards digital models of sport business.
Wojciech Cieśliński   +2 more
doaj   +1 more source

Adverse prognosis gene expression patterns in metastatic castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
We aggregated a cohort of 1012 mCRPC tissue samples from 769 patients and investigated the association of gene expression‐based pathways with clinical outcomes. Loss of AR signaling, high proliferation, and a glycolytic phenotype were independently prognostic for poor outcomes, and an adverse transcriptional feature score incorporating these pathways ...
Marina N. Sharifi   +26 more
wiley   +1 more source

Style-Shifting and Accommodative Competence in Late Middle English Written Correspondence: Putting Audience Design to the Test of Time [PDF]

open access: yes, 2018
©2018. This manuscript version is made available under the CC-BY-NC 4.0 license http://creativecommons.org/licenses/by-nc/4.0/ This document is the accepted version of a Published Work that appeared in final form in Folia Linguistica: Acta Societatis ...
García-Vidal, Tamara   +1 more
core  

Reducing Domain Gap by Reducing Style Bias [PDF]

open access: yesarXiv, 2019
Convolutional Neural Networks (CNNs) often fail to maintain their performance when they confront new test domains, which is known as the problem of domain shift. Recent studies suggest that one of the main causes of this problem is CNNs' strong inductive bias towards image styles (i.e.
arxiv  

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

open access: yesMolecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam   +9 more
wiley   +1 more source

Volume 5, Issue 1

open access: yesInternational Journal of the First Year in Higher Education, 2014
The Feature in this issue is a conversation with Richard James, a highly respected Australian academic with extensive experience in research and policy development on the First Year Experience.
Karen Nelson, John Clarke, Tracy Creagh
doaj   +1 more source

Scare-quoting and incorporation [PDF]

open access: yes, 2017
I explain a mechanism I call “incorporation,” that I think is at work in a wide range of cases often put under the heading of “scare-quoting.” Incorporation is flagging some words in one’s own utterance to indicate that they are to be interpreted as if ...
McCullagh, Mark
core  

Plasma lipidomic and metabolomic profiles in high‐grade glioma patients before and after 72‐h presurgery water‐only fasting

open access: yesMolecular Oncology, EarlyView.
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé   +7 more
wiley   +1 more source

Pension reform in Croatia [PDF]

open access: yes
Croatia's transition toward independence, and the market economy in the 1990s, exacerbated problems in the pay-as-you-go (PAYG) system, and ultimately led to its financial collapse. Although a comprehensive three-pillar reform was initiated in late 1995,
Anusic, Zoran   +2 more
core  

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