Sub-acute Toxicity Studies of Acetaminophen in Sprague Dawley Rats
The aim of the present study was to evaluate the sub-acute oral toxicity of acetaminophen in Sprague Dawley (SD) rats at 250 to 1000 mg/kg body weight (b.wt.). The following observations were noticed during the study. No mortality in male and female rats, at and up to the dose of 1000 mg/kg b.wt.
Pachaiyappan Sampath, Venkatesan +3 more
openaire +3 more sources
SUB-ACUTE DERMAL TOXICITY OF SODIUM-CONTAINING DRUGS
Drugs that have antimicrobial, anti-inflammatory and wound-healing effects deserve special attention, sodium-containing drugs are one of them, which is why they are used in veterinary medicine. The article presents the results of experimental studies to study the sub-acute toxicity of sodium-containing drugs: known – glycetinate 2%, its analogues
I. Patereha +7 more
openaire +1 more source
TOXICITY OF PREDNISOLONE, DEXAMETHASONE AND THEIR PHOTOCHEMICAL DERIVATIVES ON AQUATIC ORGANISMS [PDF]
Light exposure of aqueous suspensions of prednisolone and dexamethasone causes their partial phototransformation. The photoproducts, isolated by chromatographic techniques, have been identified by spectroscopic means.
DELLA GRECA, MARINA +6 more
core +1 more source
Review of pyronaridine anti-malarial properties and product characteristics. [PDF]
Pyronaridine was synthesized in 1970 at the Institute of Chinese Parasitic Disease and has been used in China for over 30 years for the treatment of malaria.
Arbe-Barnes, Sarah J +7 more
core +2 more sources
Bioassays with terrestrial and aquatic species as monitoring tools of hydrocarbon degradation [PDF]
In this study chemical analyses and ecotoxicity tests were applied for the assessment of a heavily hydrocarbon-contaminated soil prior and after the application of a remediation procedure that consisted in the stimulation of soil autochthonous ...
Bori Dols, Jaume +3 more
core +2 more sources
Review of the methods to determine the hazard and toxicity of pesticides to bumblebees [PDF]
Methods to determine the impact of pesticides on bumblebees are described. They are classified into laboratory tests to determine the acute toxicity and the hazard to bumblebees, (semi) field tests, and brood tests.
Steen, J.J.M., van der
core +5 more sources
The effects of two pesticides on Clarias gariepinus [PDF]
Bioassays were carried out to determine the toxicity of two pesticides, Roundup and Gramoxone on Clarias gariepinus. The acute toxicity of both pesticides decreased towards the end of the bioassay period.
Mulero, O. +2 more
core
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Evaluation of toxicity effect of Datura innoxia root extract to Clarias gariepinus fingerlings [PDF]
Clarias gariepinus fingerlings were exposed 96 hours under laboratory conditions using static bioassays with continuous aeration to determine acute toxicity of Datura innoxia root extract. The LC sub(50) of the exposed fingerlings was 128.83 mg/L.
Ayuba, V.O., Ofojekwu, P.C.
core
The microbiotest battery as an important component in the assessment of snowmelt toxicity in urban watercourses—preliminary studies [PDF]
The aim of the study was to use a battery of biotests composed of producers (Selenastrum capricornutum, Sorghum saccharatum, Lepidium sativum, and Sinapis alba), consumers (Thamnocephalus platyurus), and decomposers (Tetrahymena thermophila) to ...
Mankiewicz-Boczek, J. +3 more
core +2 more sources

