Results 21 to 30 of about 247,703 (254)

Sub-acute Toxicity Studies of Acetaminophen in Sprague Dawley Rats

open access: yesBiological and Pharmaceutical Bulletin, 2014
The aim of the present study was to evaluate the sub-acute oral toxicity of acetaminophen in Sprague Dawley (SD) rats at 250 to 1000 mg/kg body weight (b.wt.). The following observations were noticed during the study. No mortality in male and female rats, at and up to the dose of 1000 mg/kg b.wt.
Pachaiyappan Sampath, Venkatesan   +3 more
openaire   +3 more sources

SUB-ACUTE DERMAL TOXICITY OF SODIUM-CONTAINING DRUGS

open access: yesScientific and Technical Bulletin оf State Scientific Research Control Institute of Veterinary Medical Products and Fodder Additives аnd Institute of Animal Biology, 2023
Drugs that have antimicrobial, anti-inflammatory and wound-healing effects deserve special attention, sodium-containing drugs are one of them, which is why they are used in veterinary medicine. The article presents the results of experimental studies to study the sub-acute toxicity of sodium-containing drugs: known – glycetinate 2%, its analogues
I. Patereha   +7 more
openaire   +1 more source

TOXICITY OF PREDNISOLONE, DEXAMETHASONE AND THEIR PHOTOCHEMICAL DERIVATIVES ON AQUATIC ORGANISMS [PDF]

open access: yes, 2004
Light exposure of aqueous suspensions of prednisolone and dexamethasone causes their partial phototransformation. The photoproducts, isolated by chromatographic techniques, have been identified by spectroscopic means.
DELLA GRECA, MARINA   +6 more
core   +1 more source

Review of pyronaridine anti-malarial properties and product characteristics. [PDF]

open access: yes, 2012
Pyronaridine was synthesized in 1970 at the Institute of Chinese Parasitic Disease and has been used in China for over 30 years for the treatment of malaria.
Arbe-Barnes, Sarah J   +7 more
core   +2 more sources

Bioassays with terrestrial and aquatic species as monitoring tools of hydrocarbon degradation [PDF]

open access: yes, 2016
In this study chemical analyses and ecotoxicity tests were applied for the assessment of a heavily hydrocarbon-contaminated soil prior and after the application of a remediation procedure that consisted in the stimulation of soil autochthonous ...
Bori Dols, Jaume   +3 more
core   +2 more sources

Review of the methods to determine the hazard and toxicity of pesticides to bumblebees [PDF]

open access: yes, 2001
Methods to determine the impact of pesticides on bumblebees are described. They are classified into laboratory tests to determine the acute toxicity and the hazard to bumblebees, (semi) field tests, and brood tests.
Steen, J.J.M., van der
core   +5 more sources

The effects of two pesticides on Clarias gariepinus [PDF]

open access: yes, 1993
Bioassays were carried out to determine the toxicity of two pesticides, Roundup and Gramoxone on Clarias gariepinus. The acute toxicity of both pesticides decreased towards the end of the bioassay period.
Mulero, O.   +2 more
core  

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Evaluation of toxicity effect of Datura innoxia root extract to Clarias gariepinus fingerlings [PDF]

open access: yes, 2003
Clarias gariepinus fingerlings were exposed 96 hours under laboratory conditions using static bioassays with continuous aeration to determine acute toxicity of Datura innoxia root extract. The LC sub(50) of the exposed fingerlings was 128.83 mg/L.
Ayuba, V.O., Ofojekwu, P.C.
core  

The microbiotest battery as an important component in the assessment of snowmelt toxicity in urban watercourses—preliminary studies [PDF]

open access: yes, 2015
The aim of the study was to use a battery of biotests composed of producers (Selenastrum capricornutum, Sorghum saccharatum, Lepidium sativum, and Sinapis alba), consumers (Thamnocephalus platyurus), and decomposers (Tetrahymena thermophila) to ...
Mankiewicz-Boczek, J.   +3 more
core   +2 more sources

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