Results 31 to 40 of about 97,322 (245)

Investigation of the Biosafety of Antibacterial Mg(OH)₂ Nanoparticles to a Normal Biological System

Journal of Functional Biomaterials, 2023
The toxicity of Mg(OH)2 nanoparticles (NPs) as antibacterial agents to a normal biological system is unclear, so it is necessary to evaluate their potential toxic effect for safe use. In this work, the administration of these antibacterial agents did not
Ying Wang, Yanjing Liu, Xiyue Li, Fuming Wang, Yaping Huang, Yuezhou Liu, Yimin Zhu   +6 more
doaj   +1 more source

Sub-acute injection toxicity of Florfenicol VS 30

IOP Conference Series: Earth and Environmental Science, 2021
Abstract This study is aimed at identifying organs and/or target organs systems that are most sensitive to the toxic effect of the drug under study, as well as determining the level of cumulation and reversibility of pathological changes in the animal body influenced by the pharmacological substance.
A V Balyshev, M S Zhuravleva, V V Golovin, S V Abramov, M I Slozhenkina   +4 more
openaire   +1 more source

Toxicological Evaluation of Novel Cyclohexenone Derivative in an Animal Model through Histopathological and Biochemical Techniques

Toxics, 2021
Toxicity studies were conducted to provide safety data of potential drug candidates by determining lethal and toxic doses. This study was designed for pre-clinical evaluation of novel cyclohexenone derivative with respect to the acute and sub-acute ...
Muhammad Kamil, Arifa Fatima, Sami Ullah, Gowhar Ali, Rasool Khan, Naila Ismail, Mughal Qayum, Marius Irimie, Catalina Georgeta Dinu, Hanadi Talal Ahmedah, Maria Elena Cocuz   +10 more
doaj   +1 more source

Sub-acute oral toxicity study with fullerene C60 in rats

The Journal of Toxicological Sciences, 2012
To obtain initial information on the possible repeated-dose oral toxicity of fullerene C60, Crl:CD(SD) rats were administered fullerene C60 by gavage once daily at 0 (vehicle: corn oil), 1, 10, 100, or 1,000 mg/kg/day for 29 days, followed by a 14-day recovery period. No deaths occurred in any groups, and there were no changes from controls in detailed
Takahashi, Mika, Kato, Hina, Doi, Yuko, Hagiwara, Akihiro, Hirata-Koizumi, Mutsuko, Ono, Atsushi, Kubota, Reiji, Nishimura, Tetsuji, Hirose, Akihiko   +8 more
openaire   +3 more sources

TOCOSH FLOUR (Solanum tuberosum L.): A Toxicological Assessment of Traditional Peruvian Fermented Potatoes

Foods, 2020
Potato tocosh is a naturally processed potato for nutritional and curative purposes from traditional Peruvian medicine. The aim of this study was to investigate the acute and sub-acute toxicity of tocosh flour (TF).
Jonas Roberto Velasco-Chong, Oscar Herrera-Calderón, Juan Pedro Rojas-Armas, Renán Dilton Hañari-Quispe, Linder Figueroa-Salvador, Gilmar Peña-Rojas, Vidalina Andía-Ayme, Ricardo Ángel Yuli-Posadas, Andres F. Yepes-Perez, Cristian Aguilar   +9 more
doaj   +1 more source

Sub-acute Toxicity Studies of Acetaminophen in Sprague Dawley Rats

Biological and Pharmaceutical Bulletin, 2014
The aim of the present study was to evaluate the sub-acute oral toxicity of acetaminophen in Sprague Dawley (SD) rats at 250 to 1000 mg/kg body weight (b.wt.). The following observations were noticed during the study. No mortality in male and female rats, at and up to the dose of 1000 mg/kg b.wt.
Venkatesan, Pachaiyappan Sampath, Deecaraman, Munuswamy, Vijayalakshmi, Melanathuru, Sakthivelan, Sigamany Masilamani   +3 more
openaire   +3 more sources

Safety of AYUSH OSTO in experimental animals

International Journal of Ayurveda Research
Background: AYUSH OSTO is a coded formulation developed by the Central Council for Research in Ayurvedic Sciences for the treatment of bone-related disorders. Aim: The present study focused on evaluating the safety of AYUSH OSTO through acute, 28-day sub-
Sudesh N. Gaidhani, M. M. Padhi, Arjun Singh, Viswanth Reddy, Srikanth Ala   +4 more
doaj   +1 more source

Phytochemistry and toxicological assessment of Bryonia dioica roots used in north-African alternative medicine

Open Chemistry, 2019
To investigate the phytochemical composition, acute and sub-acute toxicity of the aqueous extract of B. dioica roots. The phytochemical analysis was performed using gas chromatography-mass spectrometry (GC-MS).
Bourhia Mohammed, Bari Ahmed, Ali Syed Saeed, Benbacer Laila, khlil Naima   +4 more
doaj   +1 more source

Toxicological evaluation and preliminary phytochemical characterisation of a Nigerian Cannabis sativa chemovar [PDF]

Iranian Journal of Basic Medical Sciences
Objective(s): Different Cannabis sativa chemovars produce diverse pharmacological and behavioral effects. With the widespread use of cannabis in Nigeria, detailed toxicological effects of Nigerian chemovars are lacking.
Ebele Ajagun, Babatunde Alabi, Abdul-musawwir Alli-oluwafuyi, Mary Ologe   +3 more
doaj   +1 more source

Sub-Acute Toxicity Study of Graphene Oxide in the Sprague-Dawley Rat. [PDF]

Int J Environ Res Public Health, 2016
Graphene oxide (GO) is an oxidized derivative of graphene used in biotechnology and medicine. The safety of GO is uncertain, so we evaluated its toxicity in male rats. Rat tail veins were injected with 2.5, 5, or 10 mg/kg GO for seven days and behavioral patterns, pathology, and tissue morphology were assessed. Data show that behaviors were not altered
Li Y, Wang Y, Tu L, Chen D, Luo Z, Liu D, Miao Z, Feng G, Qing L, Wang S.   +9 more
europepmc   +4 more sources