Results 1 to 10 of about 235,370 (139)

Sub-chronic toxicity study of green peas protein hydrolysate in rats. [PDF]

open access: yesToxicol Rep, 2022
Despite green peas protein hydrolysate benefits, very few studies have described the potential toxicity. The acute oral toxicity of green peas protein which hydrolyzed by bromelain at a single dose of 5000 mg/kg BW has been evaluated in Swiss Webster mice and did not produce treatment-related signs of toxicity or mortality in any of the animals tested ...
Hidayat M   +4 more
europepmc   +4 more sources

Acute and sub-chronic toxicity of Cajanus cajan leaf extracts. [PDF]

open access: yesPharm Biol, 2017
Context: The leaves of Cajanus cajan (L.) Millsp. (Fabaceae) have diverse bioactivities, but little safety data are reported. Objective: This study examines the toxicological profiles of C. cajan leaf extracts. Materials and methods: The leaves were extracted by water or 90% ethanol to obtain water or ethanol extract (WEC or EEC).
Tang R   +5 more
europepmc   +5 more sources

Sub-chronic toxicity of gold nanoparticles in male mice.

open access: yesAdv Biomed Res, 2015
Gold nanoparticles have many industrial applications; moreover, they are photothermic agents for clinical treatment of cancer. This study was provided to investigate the effects associated with different doses of applied gold nanoparticles by injection and contact procedures on the alterations of the serum levels and certain factors in male mice.72 ...
Ajdary M, Ghahnavieh MZ, Naghsh N.
europepmc   +4 more sources

Sub-chronic oral toxicity screening of quercetin in mice

open access: yesBMC Complementary Medicine and Therapies, 2022
Abstract Background Quercetin is an organic flavonoid present in several fruits and vegetables. The anti-inflammatory, antiviral, antioxidant, cardio-protective, anti-carcinogenic and neuroprotective properties demonstrated by this dietary supplement endorses it as a possible treatment for inflammatory diseases and ...
Patrice Cunningham   +10 more
openaire   +3 more sources

Acute, sub-acute, sub-chronic and chronic toxicity studies of four important Nigerian ethnomedicinal plants in rats [PDF]

open access: yesClinical Phytoscience, 2021
Resumen Antecedentes Azadirachta indica , Khaya senegalensis , Anogeissus leiocarpus y Tamarindus indica son importantes plantas etnomedicinales utilizadas para la mitigación de la salud desde la historia de la humanidad. Se utilizan discrecionalmente en la medicina folclórica bajo la premisa de que son productos naturales desprovistos de conservantes ...
Abdullah Tauheed   +5 more
openaire   +3 more sources

Monte Carlo Models for Sub-Chronic Repeated-Dose Toxicity: Systemic and Organ-Specific Toxicity

open access: yesInternational Journal of Molecular Sciences, 2022
The risk-characterization of chemicals requires the determination of repeated-dose toxicity (RDT). This depends on two main outcomes: the no-observed-adverse-effect level (NOAEL) and the lowest-observed-adverse-effect level (LOAEL). These endpoints are fundamental requirements in several regulatory frameworks, such as the Registration, Evaluation ...
Gianluca Selvestrel   +7 more
openaire   +2 more sources

Thallium Induced Sub-chronic Toxicity Profile in Wistar Rats

open access: yesIndian Journal of Veterinary Sciences & Biotechnology, 2022
Thallium (Tl) is one of the most toxic heavy metals affecting both humans and animals, yet is one of the least studied for its toxicological effects. A total of 40 male Wistar rats were randomly divided into four Groups with 10 rats in each  Group. Group I received distilled water only and served as a control.
Parvez I. Sindhi   +6 more
openaire   +1 more source

Aquatic Effects of a Localized Oil Spill on Lake Conway, AR and Its Tributaries [PDF]

open access: yes, 2015
Oil spills, no matter where they occur, elicit environmental concern and avoiding these disasters should be a priority. Old pipelines that are not regularly maintained and carry large amounts of crude oil long distances are of particular concern.
Bouldin, J. L., Kennon, M. E.
core   +3 more sources

The surface reactivity of iron oxide nanoparticles as a potential hazard for aquatic environments: A study on Daphnia magna adults and embryos [PDF]

open access: yes, 2018
open5noNano-ecotoxicology is extensively debated and nanomaterial surface reactivity is an emerging topic. Iron oxide nanoparticles are widely applied, with organic or inorganic coatings for stabilizing their suspensions.

core   +1 more source

An overview of anti-diabetic plants used in Gabon: Pharmacology and Toxicology [PDF]

open access: yes, 2018
© 2017 Elsevier B.V. All rights reserved.Ethnopharmacological relevance: The management of diabetes mellitus management in African communities, especially in Gabon, is not well established as more than 60% of population rely on traditional treatments as ...
A. Souza   +374 more
core   +4 more sources

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