Results 11 to 20 of about 3,864,827 (278)

Evaluation of Acute and Sub-Chronic Toxicity of Lactobacillus rhamnosus GG in Sprague-Dawley Rats [PDF]

Advanced Biomedical Research
Background: Probiotic-based bacteriotherapy has emerged as a potentially effective strategy for preventing infectious diseases. Lactobacillus strains consumed as probiotics and the safety of these spp.
Vedam Venkata Kanthi Vaishnavi, Urmila Banik, Gokul Shankar Sabesan, Arun K. Adhikary, Subramani Parasuraman   +4 more
doaj   +3 more sources

Monte Carlo Models for Sub-Chronic Repeated-Dose Toxicity: Systemic and Organ-Specific Toxicity

International Journal of Molecular Sciences, 2022
The risk-characterization of chemicals requires the determination of repeated-dose toxicity (RDT). This depends on two main outcomes: the no-observed-adverse-effect level (NOAEL) and the lowest-observed-adverse-effect level (LOAEL). These endpoints are fundamental requirements in several regulatory frameworks, such as the Registration, Evaluation ...
Andrey A Toropov, Domenico Gadaleta, Emilio Benfenati   +2 more
exaly   +4 more sources

Evaluation of acute and sub-chronic toxicity of lithothamnion sp. in mice and rats. [PDF]

Toxicol Rep, 2020
Lithothamnion sp., a red algae of the Corallinaceae family, when harvested in its calcareous form, is rich in calcium, magnesium and a variety of trace minerals. It is used as a beneficial dietary mineral supplement across the world (Aquamin F). This study was designed to evaluate the acute and sub-chronic toxicity of Lithothamnion sp. according to the
Zhang Y, Tian R, Wu H, Li X, Li S, Bian L.   +5 more
europepmc   +5 more sources

A botanical from the antiproliferative Cameroonian spice, Imperata cylindrica is safe at lower doses, as demonstrated by oral acute and sub-chronic toxicity screenings [PDF]

BMC Complementary Medicine and Therapies, 2020
Background The cytotoxicity of the root’s methanol extract of Imperata cylindrica (ICR). was previously reported in a panel of human cancer cell lines, including multi-drug resistant phenotypes.
Paul Nayim, Armelle T. Mbaveng, Arsene M. Ntyam, Victor Kuete   +3 more
doaj   +2 more sources

Nanobubble Ozone Stored in Hyaluronic Acid-Decorated Liposome Solutions: Inactivating Antibiotic-Resistant Bacteria and Genotoxicity, Sub-Acute and Sub-Chronic Toxicity Tests [PDF]

Infection and Drug Resistance
Perihan Erkan Alkan,1 Talha Karabiyik2 1Department of Medical Microbiology, Faculty of Medicine, Bandırma Onyedi Eylül University, Bandırma,/Balıkesir, Turkey; 2Department of Medical Biochemistry, Faculty of Medicine, Bandırma
Erkan Alkan P, Karabiyik T
doaj   +2 more sources

Sub chronic toxicity studies of lactulose in rats.

Indian journal of experimental biology, 2001
Lactulose has profound health benefits by way of increasing bifidobacterial flora in the intestine of infants thereby protecting them against enteric infection, constipation and systemic encephalopathy. In the present study to assess the sub chronic toxicity of lactulose syrup, the rats were fed on a basal feed supplemented with lactulose syrup at 0.5,
V, Baskaran, K N, Murthy, , Mahadevamma, S, Vishwanatha, B R, Lokesh   +4 more
core   +3 more sources

Sub-Chronic Microcystin-LR Liver Toxicity in Preexisting Diet-Induced Nonalcoholic Steatohepatitis in Rats

Toxins, 2019
Microcystin-LR (MCLR) is a hepatotoxic cyanotoxin reported to cause a phenotype similar to nonalcoholic steatohepatitis (NASH). NASH is a common progressive liver disease that advances in severity due to exogenous stressors such as poor diet and toxicant
Tarana Arman, Katherine D. Lynch, Michelle L. Montonye, Michael Goedken, John D. Clarke   +4 more
doaj   +3 more sources

Dose and time-dependent sub-chronic toxicity study of hydroethanolic leaf extract of Flabellaria paniculata Cav. (Malpighiaceae) in rodents

Frontiers in Pharmacology, 2014
Flabellaria paniculata Cav. (Malpighiaceae) is a climbing shrub, the preparations of which are used in the treatment of wounds and ulcers in Nigeria and Ghana. This study investigated the sub-chronic toxicity profile of the hydroethanolic leaf extract of
Abidemi James Akindele, Adejuwon Adewale Adeneye, Oluwole Saidi Salau, Margaret Oluwatoyin Sofidiya, Adokiye Senibo Benebo   +4 more
doaj   +3 more sources

Acute and Sub-Chronic Toxicity Effects of Methanol Extract of Pyrenacantha staudtii Hutch and Dale (Icacinaceae) in Wistar Rats

Journal of Applied Sciences and Environmental Management
Pyrenacantha staudtii has been used for its medicinal purposes especially in Africa and these supposed activities have been investigated scientifically, but the safety of this plant has not been established.
A. Falodun, O. Esosuota, S. Aghahowa, O. Erharuyi, I. Akhigbe, V. Imieje   +5 more
doaj   +1 more source

Acute and sub-chronic oral toxicity study of purple sweet potato (Ipomoea batatas [L.] Lam) yogurt in mice (Mus musculus) [PDF]

Veterinary World, 2022
Background and Aim: Food safety is an important aspect to be evaluated in preventing any potentially harmful side effects of food product such as yogurt. The purple sweet potato yogurt product was developed to combine the benefits of probiotic activities
Astrid Feinisa Khairani, Yunisa Pamela, Nandina Oktavia, Achadiyani Achadiyani, M. Yusuf Adipraja, Prita Yasri Zhafira, Widad Aghnia Shalannandia, Nur Atik   +7 more
doaj   +1 more source