Results 1 to 10 of about 3,864,827 (278)

Acute and sub-chronic toxicity of Cajanus cajan leaf extracts [PDF]

Pharmaceutical Biology, 2017
Context: The leaves of Cajanus cajan (L.) Millsp. (Fabaceae) have diverse bioactivities, but little safety data are reported. Objective: This study examines the toxicological profiles of C. cajan leaf extracts.
Rong Tang, Ru-hua Tian, Jia-zhong Cai, Jun-hui Wu, Xiao-ling Shen, Ying-jie Hu   +5 more
doaj   +6 more sources

Acute and sub-chronic toxicity of Liberin, an anti-diabetic polyherbal formulation in rats [PDF]

Journal of Ayurveda and Integrative Medicine, 2023
Background: The polyherbal formulation (PHF) liberin, is known to exert anti-hyperglycemic effects in type 2 diabetes mellitus. Hence, it is important to study the safety profile of PHF in the current study through acute and chronic toxicity evaluation ...
Renuka Suvarna, Varashree Bolar Suryakanth, Pugazhandhi Bakthavatchalam, Guruprasad Kalthur, Deepak Nayak M, M. Mukhyaprana Prabhu, Basavaraj S. Hadapad, Revathi P. Shenoy   +7 more
doaj   +3 more sources

Sub-chronic toxicity study of green peas protein hydrolysate in rats [PDF]

Toxicology Reports, 2022
Despite green peas protein hydrolysate benefits, very few studies have described the potential toxicity. The acute oral toxicity of green peas protein which hydrolyzed by bromelain at a single dose of 5000 mg/kg BW has been evaluated in Swiss Webster ...
Meilinah Hidayat, Sijani Prahastuti, Anggie S. Rakasiwi, Sipra Prisilia, Khomaini Hasan   +4 more
doaj   +4 more sources

Acute and sub-chronic toxicity study of novel polyherbal formulation in non-alcoholic fatty liver using Wistar rats [PDF]

Future Science OA
Aim: This study assessed the acute and sub-chronic toxicity of a novel polyherbal formulation tablet in Wistar rats Materials & methods: Acute toxicity and sub-chronic toxicity was assessed following OECD (Organisation for the Economic Co-operation and ...
Anuragh Singh, K Ilango
doaj   +4 more sources

Biocompatibility and sub-chronic toxicity studies of phlorotannin/polycaprolactone coated trachea tube for advancing medical device applications [PDF]

Scientific Reports
The phlorotannin-polycaprolactone-coated endotracheal tube (PP tube) has been developed with the aim of preventing tracheal stenosis that can result from endotracheal intubation, a factor that can lead to a serious airway obstruction.
Tae-Hee Kim, Seong-Yeong Heo, Gun-Woo Oh, Won Sun Park, Won-Kyo Jung   +4 more
doaj   +3 more sources

Sub-chronic toxicity of gold nanoparticles in male mice

Advanced Biomedical Research, 2015
Background: Gold nanoparticles have many industrial applications; moreover, they are photothermic agents for clinical treatment of cancer. This study was provided to investigate the effects associated with different doses of applied gold nanoparticles by
Marziyeh Ajdary, Marziyeh Ziaee Ghahnavieh, Nooshin Naghsh   +2 more
doaj   +4 more sources

Sub-acute and sub-chronic toxicity assessment of the antimicrobial peptide Dermaseptin B2 on biochemical, haematological and histopathological parameters in BALB/c mice and Albino Wistar rats [PDF]

Heliyon, 2022
Background: Dermaseptins (Drs) are peptides found in the skin secretions of a variety of Hylid frogs, particularly those belonging to the Agalychnis and Phyllomedusa families. Dermaseptin B2 (Drs B2), an amphipathic, α-helical polypeptide was reported as
Ahmed A. Abdille, Shedrack Reuben Kitimu, Mark M. Ndubi, Josephine Kimani, Esther N. Maina, Wallace Bulimo, Yahaya Gavamukulya, Fred Wamunyokoli   +7 more
doaj   +2 more sources

Sub-chronic oral toxicity screening of quercetin in mice

BMC Complementary Medicine and Therapies, 2022
Background Quercetin is an organic flavonoid present in several fruits and vegetables. The anti-inflammatory, antiviral, antioxidant, cardio-protective, anti-carcinogenic and neuroprotective properties demonstrated by this dietary supplement endorses it ...
Patrice Cunningham, Emma Patton, Brandon N. VanderVeen, Christian Unger, Ahmed Aladhami, Reilly T. Enos, Sarah Madero, Ioulia Chatzistamou, Daping Fan, E. Angela Murphy, Kandy T. Velázquez   +10 more
doaj   +3 more sources

Stevia rebaudiana extract (main components: chlorogenic acid and its analogues) as a new safe feed additive: evaluation of acute toxicity, sub chronic toxicity, genotoxicity, and teratogenicity [PDF]

Frontiers in Veterinary Science
IntroductionStevia rebaudiana extract (SREC), primarily composed of chlorogenic acid and its analogues, is a promising feed additive with potential benefits for livestock performance, gut health, and antioxidant capacity.
Yuting Li, Liping Zhu, Dongsheng He, Ling Fang, Yajing Li, Shusheng Tang   +5 more
doaj   +2 more sources

Evaluation of acute and sub-chronic toxicity of bitter melon seed extract in Wistar rats [PDF]

Toxicology Reports, 2022
Pharmacological studies have revealed the potential antidiabetic effects of bitter melon seeds (Momordica charantia) in animals and humans. However, the sub-chronic safety of bitter melon seeds remains elusive.
Wan-Yu Chung, Sudhakar Jadhav, Pang-Kuei Hsu, Chen-Meng Kuan   +3 more
doaj   +2 more sources