Results 41 to 50 of about 3,864,827 (278)

Safety of AYUSH OSTO in experimental animals

open access: yesInternational Journal of Ayurveda Research
Background: AYUSH OSTO is a coded formulation developed by the Central Council for Research in Ayurvedic Sciences for the treatment of bone-related disorders. Aim: The present study focused on evaluating the safety of AYUSH OSTO through acute, 28-day sub-
Sudesh N. Gaidhani   +4 more
doaj   +1 more source

Sub-chronic safety evaluation of aqueous extract of Alangium salvifolium (L.f.) Wangerin leaves in rats

open access: yesJournal of Advanced Pharmaceutical Technology & Research, 2017
Conventionally, the juice and extract of Alangium salvifolium leaves have been used for the treatment of diabetes, wound healing, dog bite, and as a poultice in rheumatism.
Bhupinder Kapoor   +3 more
doaj   +1 more source

Toxicological assessment of the hydroethanolic leaf extract of ''Clerodendrum capitatum'' in Wistar rats

open access: yesThe Pan African Medical Journal, 2016
INTRODUCTION: ''Clerodendrum capitatum''(Willd) Schumach. and Thonn (Lamiaceae) is used in African traditional medicine for the treatment of malaria, hypertension, obesity, jaundice and diabetes however there is lack of experimental data on its possible ...
Kokou Idoh   +3 more
doaj   +1 more source

Sub-chronic Oral Toxicity of a Water-Soluble Extract of Centella asiatica(Centell-S) in Wistar Rats (Tables)

open access: yes, 2023
Background: Centell-S is a standardized water-soluble extract of Centella asiatica containing more than 80% w/w triterpenoid glycosides. Madecassoside and asiaticoside are two major bioactive components of the extract.
Supawit Tangpanithandee (17416305)
core   +1 more source

Toxicity assessment of sub-acute and sub-chronic oral administration and diuretic potential of aqueous extract of Hibiscus sabdariffa calyces

open access: yesHeliyon, 2020
Background: Food and herbal usage of Hibiscus sabdariffa (HS) is attaining improved global relevance and acceptance without recourse to its potential toxic effects.
N.S. Njinga   +12 more
doaj   +1 more source

Hematological and biochemical effects of sub-chronic artesunate exposure in rats

open access: yesToxicology Reports, 2015
Artesunate is a potent and rapidly acting blood schizontocide used to treat chloroquine resistant malaria. Artesunate has been reported to cause embryo, reduced reproductive capacity, hepatotoxicity, neurotoxicity and hematological abnormalities ...
Papiya Bigoniya   +2 more
doaj   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo   +5 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Toxic Effects of Lead Exposure on Freshwater Climbing Perch, Anabas testudineus, and Bioremediation Using Ocimum sanctum Leaf Powder

open access: yesToxics
The acute and chronic toxicity of lead to Anabas testudineus was determined in this study using static replacement bioassay testing. During the chronic toxicity studies, an experiment on the bioremediation of lead toxicity using Ocimum sanctum leaf ...
Nimai Chandra Saha   +6 more
doaj   +1 more source

Acute and sub-chronic toxicological evaluation of the herbal product HAD-B1 in Beagle dogs

open access: yesToxicology Reports, 2021
HAD-B1 is a herbal formula originated from Korean Traditional Medicine that used to treat lung cancer patients. Herein we assessed acute and sub-chronic toxicity of HAD-B1 in beagle dogs. Acute study, 4 weeks dose rate finding (DRF) study and sub chronic
Si-Yeon Song   +5 more
doaj   +1 more source

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